Enhancement of Hair Growth Through Stimulation of Hair Follicle Stem Cells by Prostaglandin E2 Collagen Matrix

    November 2022 in “ Experimental cell research ”
    Hui Cheng, Fei Liu, Manqian Zhou … Hong Cai
    Studysummary This study found that a PGE2 matrix, when injected subcutaneously, increased the proportion of developing hair follicles and improved hair follicle stem cell markers in a mouse model of hair loss.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 36

    1. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence Nature · 2021
    2. Expansion And Characterization Of Epithelial Stem Cells With Potential For Cyclical Hair Regeneration Scientific Reports · 2021
    3. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    4. Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride JAMA Dermatology · 2020
    5. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    6. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    7. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    8. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    9. Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date Drug Design Development and Therapy · 2020
    10. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
    11. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    12. HMGB1 Promotes Hair Growth via the Modulation of Prostaglandin Metabolism Scientific Reports · 2019
    13. Sustained Human Hair Follicle Growth Ex Vivo in a Glycosaminoglycan Hydrogel Matrix International journal of molecular sciences · 2019
    14. Mechanical Stretch Induces Hair Regeneration Through the Alternative Activation of Macrophages Nature Communications · 2019
    15. A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth ACS nano · 2019
    16. The Balance of BMP6 and WNT10B Regulates the Telogen-Anagen Transition of Hair Follicles Cell Communication and Signaling · 2019
    17. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    18. Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders Acta dermato-venereologica · 2017
    19. Efficacy of Topical Latanoprost Versus Minoxidil and Betamethasone Valerate on the Treatment of Alopecia Areata Journal of Dermatological Treatment · 2017
    20. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    21. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    22. Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2016
    23. Promising Alternative Clinical Uses of Prostaglandin F2α Analogs: Beyond the Eyelashes Journal of The American Academy of Dermatology · 2015
    24. Evaluation and Diagnosis of the Hair Loss Patient Journal of The American Academy of Dermatology · 2014
    25. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44 Journal of Investigative Dermatology · 2012
    26. Hairy Tale of Signaling in Hair Follicle Development and Cycling Seminars in cell & developmental biology · 2012
    27. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    28. Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a Journal of Dermatological Science · 2010
    29. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    30. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    31. Prostaglandin Metabolism in Human Hair Follicle Experimental Dermatology · 2007
    32. Influence of Prostaglandin F2α and Its Analogues on Hair Regrowth and Follicular Melanogenesis in a Murine Model Experimental dermatology · 2005
    33. Prostaglandin-Induced Hair Growth Survey of Ophthalmology · 2002
    34. Effect of Latanoprost on Hair Growth in the Bald Scalp of the Stump-Tailed Macaque: A Pilot Study 2002
    35. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997
    36. Cytokines and Growth Factors Influence Hair Growth In Vitro: Possible Implications for the Pathogenesis and Treatment of Alopecia Areata Archives of Dermatological Research · 1996

    Related research 1

    1. 15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth Naunyn-Schmiedeberg's Archives of Pharmacology · 2016