Dutasteride as an Effective Treatment in Androgenetic Alopecia: A Literature Review

    Dawid Sewruk, Karol Kanon, Mathias Spitaleri … Julia Głowacka
    Studysummary This review found that dutasteride is more effective than finasteride in increasing hair count and shaft thickness for androgenetic alopecia in men, with potential for reduced systemic side effects through mesotherapy, although further research is needed on long-term safety and dosage.
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    Research cited in this study 26

    1. Evaluating 5 Alpha Reductase Inhibitors for the Treatment of Male Androgenic Alopecia Expert Opinion on Pharmacotherapy · 2023
    2. Comparing Current Therapeutic Modalities of Androgenic Alopecia: A Literature Review of Clinical Trials Cureus · 2023
    3. Use of 5-Alpha Reductase Inhibitors in Dermatology: A Narrative Review Dermatology and Therapy · 2023
    4. Understanding Causes of Hair Loss in Women Dermatologic Clinics · 2021
    5. Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls Clinical Interventions in Aging · 2021
    6. Hair Transplantation: Basic Overview Journal of The American Academy of Dermatology · 2021
    7. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality Journal of Dermatological Treatment · 2020
    8. Efficacy of Intralesional and Oral Dutasteride in the Treatment of Androgenetic Alopecia: A Systematic Review Skin appendage disorders · 2020
    9. Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm The World Journal of Men's Health · 2020
    10. A Review on Finasteride: A 5-Alpha Reductase Inhibitor, Its Mechanism, Facts, and Benefits Journal of Drug Delivery and Therapeutics · 2019
    11. The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis Clinical Interventions in Aging · 2019
    12. Androgenic Alopecia: The Risk–Benefit Ratio of Finasteride Journal of Mind and Medical Sciences · 2018
    13. Androgenetic Alopecia: A Review Endocrine · 2017
    14. Mesotherapy with Dutasteride in the Treatment of Androgenetic Alopecia International Journal of Trichology · 2017
    15. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    16. A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2014
    17. Evaluation of the Effect of Injection of Dutasteride as a Mesotherapeutic Tool in the Treatment of Androgenetic Alopecia in Males Our Dermatology Online · 2013
    18. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    19. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011
    20. Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study Journal of The American Academy of Dermatology · 2010
    21. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    22. Dutasteride Drugs · 2008
    23. Dutasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins Journal of Cosmetic Dermatology · 2007
    24. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    25. The Genetics of Androgenetic Alopecia Clinics in Dermatology · 2001
    26. Androgenetic Alopecia and Microinflammation International Journal of Dermatology · 2000

    Related research 6

    1. Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review Brazilian Journal of Hair Health · 2024
    2. Evaluation of the Therapeutic Effects of AGA Drugs by Measuring Finasteride, Dutasteride, and Dihydrotestosterone in Hair Clinica Chimica Acta · 2023
    3. What Do We Know About 5-Alpha Reductase Inhibitors? Surgical and Cosmetic Dermatology · 2018
    4. Dutasteride in Androgenetic Alopecia: An Update Current Clinical Pharmacology · 2017
    5. Dutasteride for Men with Androgenic Alopecia Unresponsive to Finasteride Journal of Investigative Dermatology · 2016
    6. The Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice The FASEB Journal · 2013