Hair Follicle-Targeted Delivery of Azelaic Acid Micro/Nanocrystals Promotes the Treatment of Acne Vulgaris

    Jun Yan, Haorong Li, J. Li … Wenting Song
    Studysummary This study highlights that current research efforts to deliver anti-acne drugs to hair follicles have primarily targeted healthy follicles, overlooking the distinct characteristics of pathologically clogged follicles in acne vulgaris.
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    Research cited in this study 11

    1. Nanoparticles for Topical Application in the Treatment of Skin Dysfunctions: An Overview of Dermo-Cosmetic and Dermatological Products International Journal of Molecular Sciences · 2022
    2. Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders Asian Journal of Pharmaceutical Sciences · 2022
    3. Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles Colloids and surfaces. B, Biointerfaces · 2021
    4. Thiolated and PEGylated Silica Nanoparticle Delivery to Hair Follicles International journal of pharmaceutics · 2020
    5. Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus International Journal of Biological Macromolecules · 2020
    6. Selective Delivery of Adapalene to the Human Hair Follicle Under Finite Dose Conditions Using Polymeric Micelle Nanocarriers Nanoscale · 2017
    7. Histological Evaluation of Follicular Delivery of Arginine via Nanostructured Lipid Carriers: A Novel Potential Approach for the Treatment of Alopecia Artificial Cells Nanomedicine and Biotechnology · 2016
    8. Permeation of Topically Applied Magnesium Ions Through Human Skin Is Facilitated by Hair Follicles Magnesium research · 2016
    9. Intradermal and Follicular Delivery of Adapalene Liposomes Drug development and industrial pharmacy · 2015
    10. Analysis of Hair Follicle Penetration of Lidocaine and Fluorescein Isothiocyanate-Dextran 4 kDa Using Hair Follicle-Plugging Method Drug Development and Industrial Pharmacy · 2013
    11. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011