58 citations,
March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv” Hormones and signaling pathways control sebaceous gland function and could help treat acne.
55 citations,
August 2013 in “PloS one” Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.
48 citations,
September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
48 citations,
April 2015 in “PLOS ONE” Excessive hair growth affects the quality of life of Iranian women with PCOS the most.
42 citations,
May 2016 in “American Journal of Clinical Dermatology” Using platelet-rich plasma, which is full of growth factors, can help treat pattern hair loss.
37 citations,
February 2010 in “Psychoneuroendocrinology” Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
36 citations,
June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
33 citations,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
32 citations,
April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
31 citations,
July 2017 in “Stem cell investigation” Platelet-rich plasma (PRP) is a simple, cost-effective treatment that promotes hair growth and reduces hair loss, with high patient satisfaction.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
30 citations,
November 2019 in “Genetics selection evolution” Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.
27 citations,
January 2017 in “Indian Dermatology Online Journal” PRP injections can help increase hair density and thickness in men with hair loss.
27 citations,
August 2008 in “Mayo Clinic proceedings” Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.
26 citations,
October 2016 in “American journal of clinical dermatology” New treatments like JAK inhibitors show promise for reversing alopecia areata.
26 citations,
January 2016 in “Journal of cutaneous and aesthetic surgery” Hair transplant combining scalp and beard hair with PRP was successful for scarring alopecia.
25 citations,
April 2017 in “PloS one” Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.
25 citations,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
25 citations,
June 2015 in “Acta dermato-venereologica” Methotrexate can help some kids with severe hair loss regrow hair.
23 citations,
May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
22 citations,
January 2017 in “Indian Dermatology Online Journal” Body hair transplants can treat baldness but differ from scalp hair and need more research on long-term results and side effects.
22 citations,
July 2014 in “Hormones” Metformin may help treat neuroendocrine tumors.
19 citations,
January 2017 in “International Journal of Trichology” The document concludes that injecting platelet-rich plasma can effectively treat androgenetic alopecia, a type of hair loss.
18 citations,
March 2022 in “Drug design, development and therapy” Platelet-rich plasma (PRP) may help with various hair loss types, but more research is needed to find the best use method.
18 citations,
April 2021 in “PLOS ONE” The review concluded that reporting on PRP therapy is often incomplete, leading to uncertainty about its effectiveness.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
18 citations,
January 2019 in “International Journal of Trichology” PRP therapy works better than minoxidil for treating hair loss.
18 citations,
August 2017 in “PLOS ONE” Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.