Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses Alopecia X in plush-coated dogs, noting that while treatments like melatonin and laser therapy have shown promise, the condition is generally considered a cosmetic issue without the need for therapy.

This study found that PCL-based nanofiber scaffolds enhanced cell proliferation and extracellular matrix deposition, suggesting they show promise as a cell delivery system for improving skin wound healing.

This study demonstrated the feasibility of a new patient-controlled method for tissue expansion that achieved full expansion in about 3 weeks with minimal complications after mastectomy.

This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.

This case report discusses a rare occurrence of systemic sclerosis with lupus erythematosus panniculitis in a Japanese patient and highlights hydroxychloroquine as a potential treatment, noting a dramatic improvement.

Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.

This study describes a protocol for generating a fully functional 3D integumentary organ system from murine induced pluripotent stem cells, including the formation of hair follicles and sebaceous glands that function in vivo.

This study found that early passage dermal papilla cell-derived extracellular vesicles, combined with specialized medium, helped adipose-derived stem cells develop dermal papilla-like properties.

This study found that using calcipotriene and betamethasone dipropionate cream in a real-world setting significantly improved clinical outcomes and patient quality of life for adults with mild-to-moderate scalp psoriasis, especially among those with higher adherence, demonstrating high treatment satisfaction.

In this study, dermal papilla cell-derived exosomes accelerated hair follicle growth in mice, suggesting potential for treating hair loss by modulating key signaling pathways.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.

This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.

Daclizumab may cause psoriasis-like skin problems in multiple sclerosis patients.

This study reports that adipose mesenchymal stem cell-derived exosomes and platelet-rich plasma both improved the condition of photoaged facial skin, with no significant difference in effectiveness between the two treatments, potentially offering a quicker and less invasive option for patients.

In this study, researchers modified an acellular scaffold with different concentrations of eggshell membrane protein, finding that a 5% concentration effectively enhanced tissue regeneration in mice with excisional wounds, achieving complete healing within 14 days without causing immunogenicity or inflammation.

In this study, Eclipta alba phytosomes were developed to enhance the bioavailability and therapeutic efficacy of its bioactive compounds, showing improved in vitro antioxidant activity and significant in vivo anticancer effects compared to the free extract.

Females are more prone to lupus and arthritis due to X chromosome factors.

In this study, a new IPL device effectively reduced hair regrowth with high patient satisfaction, particularly in individuals with coarse dark hair and darker skin, despite repeated sessions needed for lighter hair and skin.

This review highlights that exosomes from adipose-derived stem cells, particularly those enriched with circ-Ash1l, can inhibit ferroptosis and reduce UVB-induced skin aging by delivering GPX4-promoting signals to damaged cells, thus offering a potential regenerative therapy for photoaged skin.

This review discusses the development and use of various animal models for studying psoriasis, highlighting their strengths and limitations, but reports no new experimental results.

This study found that the X-ray patterns of stretched mammalian hair (β-keratin) are similar to those of natural silk (fibrion), suggesting a similar elastic mechanism involving reversible intra-molecular transformations.

This study found that mice lacking the Sept4/ARTS gene had more hair follicle stem cells and improved wound healing, suggesting apoptosis regulation as a potential target in regenerative medicine.

This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.

This study found that topically applied liposomal spherical nucleic acids targeting the IL-17 receptor could effectively reduce psoriasis severity in preclinical models.

The researchers reported that the antipsoriatic compounds 1,25-dihydroxy-vitamin D3 and calcipotriol thinned the living cell compartment in organotypic ORS cultures by accelerating the differentiation pathway rather than affecting proliferation.

This study found that inducing SOX2 in keratinocytes significantly reduced pressure ulcer formation after cutaneous ischemia-reperfusion injury by producing amphiregulin, which also reduced oxidative stress and apoptosis.

This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.

In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.