August 2026 in “Stem Cell Research & Therapy” This review found that while MSC and EV-based therapies could potentially improve skin and hair rejuvenation, their clinical efficacy is limited by inconsistent study designs and a lack of standardization.
February 2026 in “Journal of Cosmetic Dermatology” This study found that intradermal polynucleotide injections were linked to improvements in the appearance around the eyes and increased patient satisfaction, with minimal adverse effects, suggesting potential for further research to validate efficacy and optimize treatment protocols.
January 2026 in “Dermatologic Therapy” In this systematic review and meta‐analysis, botulinum toxin monotherapy was found to significantly increase hair density in patients with androgenetic alopecia, with optimal effects observed using a 100-unit dose every six months. These findings suggest potential efficacy but should be confirmed in larger, placebo-controlled trials.
2 citations
,
November 2024 in “Aesthetic Surgery Journal” This study found that vibration anesthesia significantly reduced pain during botulinum toxin injections for masseter reduction without affecting the injection's diffusion or causing adverse effects, and high patient satisfaction was also reported.
September 2024 in “Journal of Cosmetic Dermatology” Cold gel compresses are the best for pain relief during scalp microneedling.
28 citations
,
April 2024 in “Skin Research and Technology” This review concludes that platelet-rich plasma treatments significantly improve various facial skin parameters, particularly when combined with hyaluronic acid, and stresses the need for standardized preparation protocols.
9 citations
,
July 2024 in “Toxins” This opinion article reviews various pathways through which onabotulinumtoxinA might work in medical treatments, highlighting applications beyond muscle paralysis, including pain inhibition and potential effects on hair loss and cancer cell apoptosis.
February 2024 in “Skin health and disease” This review reports that exosomes show potential in regenerative and cosmetic dermatology for applications like wound healing and hair loss mitigation, but their clinical use is currently limited by high costs, complex processing, and sparse clinical evidence.
13 citations
,
September 2022 in “Journal of Animal Behaviour and Biometeorology” This article reviews the thermoregulation mechanisms in African and Asian elephants and highlights challenges from climate change, with no new empirical results presented.
3 citations
,
July 2023 in “Plastic and reconstructive surgery/PSEF CD journals” This systematic review found that sole nanofat grafting in plastic and reconstructive surgery shows potential benefits for scar improvement and anti-aging, with increases in skin thickness, collagen, and elastic fibers, but the evidence level remains low and further research is needed.
1 citations
,
May 2007 in “Chinese Medical Journal” This case report describes a 24-year-old woman with a rare giant cerebriform pigmented nevus on the scalp, which was identified as a giant congenital intradermal nevus based on clinical and pathological findings.
January 2025 in “Journal of Cosmetic Dermatology” This source reported that early evidence supports the potential efficacy of exosomes in treating conditions like alopecia, facial rejuvenation, hyperpigmentation, and scarring, but noted that standardization issues need addressing through further studies to better understand their use in aesthetic dermatology.
April 2024 in “Journal of Investigative Dermatology” This study identified three new genetic loci linked to sweat gland density in a GWAS involving 6,210 Han Chinese individuals, highlighting potential targets for understanding conditions like anhidrosis and hyperhidrosis and emphasizing the use of quantitative traits in genetic dermatology research.
13 citations
,
November 2022 in “Future Journal of Pharmaceutical Sciences” This review examines liposome-based cosmeceuticals for various skin conditions and reports no new clinical results, highlighting the potential promise these formulations offer for future applications.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
April 2024 in “Current research in nutrition and food science” This study found that a food supplement improved skin moisturization, elasticity, and thickness, reduced telogen hair density, and enhanced nail status in women with mild-to-moderate aging signs after 84 days.
This systematic review reports positive outcomes for platelet-rich plasma in aesthetic dermatology applications like skin rejuvenation, hair restoration, wound healing, and fat grafting, but highlights the need for standardized protocols in future research.
44 citations
,
April 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the potential role of mesenchymal stromal cell-derived exosomes in skin regeneration and calls for more research to address clinical translation challenges, without reporting new results.
35 citations
,
April 2024 in “Life” This literature review explored the potential therapeutic applications of bee venom, Ficus carica, and Geranium essential oil in treating skin conditions like vitiligo, melasma, and melanoma, concluding these natural products may offer anti-inflammatory, antibacterial, and antioxidant benefits for dermatological care, especially for diabetic patients.
25 citations
,
February 2025 in “Frontiers in Bioengineering and Biotechnology” This review covers advancements in skin repair and rejuvenation technologies, highlighting potential benefits of stem cell therapy, bioengineered skin substitutes, PRP, exosome therapies, and gene editing for conditions such as chronic wounds and genetic disorders, though challenges in accessibility, safety, and long-term effectiveness remain.
25 citations
,
November 2021 in “Toxins” This review discusses the use of bee venom in skin cosmetics and highlights safety concerns related to potential immune reactions, but it reports no new clinical results.
12 citations
,
January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This systematic review describes current findings on the use of recombinant epidermal growth factor (rhEGF) for skin aging and wound healing, emphasizing its potential benefits but highlighting the need for more controlled studies to optimize dosing and treatment protocols.
5 citations
,
May 2024 in “Journal of Cosmetic Dermatology” In this study, treatment with cell-derived nanovesicles from hair follicle mesenchymal stem cells improved photoaging signs in UVB-exposed mice and human dermal fibroblasts by reducing oxidative stress, enhancing cell proliferation, and promoting extracellular matrix production.
4 citations
,
August 2025 in “Journal of Food Science” This review highlights that Tremella fuciformis polysaccharide exhibits various bioactivities, such as antioxidant and immune-modulating effects, and explores its potential applications in food, pharmaceutical, and cosmetic industries.
2 citations
,
November 2023 in “Journal of Cosmetic Dermatology” This review examines the bibliometric landscape of research on platelet-rich plasma in cosmetic therapy from 2001 to 2022 and reports no new clinical findings, but highlights research trends and future directions.
1 citations
,
April 2025 in “Journal of Cosmetic Dermatology” This study found that using Alastin Restorative Skin Complex Serum 2.0 with TriHex Technology for 12 weeks significantly improved facial skin hydration, elasticity, and overall quality in individuals with moderate to severe skin aging, with histological evidence showing new collagen and elastin fibers.
1 citations
,
January 2023 in “Frontiers in genetics” This study identified specific genetic markers related to wool quality in Rambouillet sheep, which may aid breeders in making informed selection and breeding decisions for improved fine wool production.
September 2026 in “Cureus” In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.
December 2025 in “International Journal of Molecular Sciences” In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.
This review discusses forensic DNA phenotyping and its potential applications, particularly for human identification in Latin American populations, but notes challenges due to genetic diversity and reports no new results.