Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides

    February 2026 in “ Journal of Cosmetic Dermatology ”
    Georges Ziade, Elias Keyrouz, Joy El Maalouf … Georges Fidawi
    Studysummary This study found that intradermal polynucleotide injections were linked to improvements in the appearance around the eyes and increased patient satisfaction, with minimal adverse effects, suggesting potential for further research to validate efficacy and optimize treatment protocols.
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    Research cited in this study 2

    1. Consensus Report on the Use of PN-HPT (Polynucleotides Highly Purified Technology) in Aesthetic Medicine Journal of cosmetic dermatology · 2020
    2. Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster International Journal of Molecular Sciences · 2016