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      research Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides

      February 2026 in “Journal of Cosmetic Dermatology”
      This study found that intradermal polynucleotide injections were linked to improvements in the appearance around the eyes and increased patient satisfaction, with minimal adverse effects, suggesting potential for further research to validate efficacy and optimize treatment protocols.

      research Periorbital Rejuvenation: A Review of Dermatologic Treatments

      79 citations , January 1999 in “Dermatologic surgery”
      This review discusses various dermatologic treatments for periorbital skin rejuvenation but reports no new clinical results; it highlights the importance of patient selection and aging severity in choosing appropriate therapies.

      research Laser Treatment of Skin Texture and Fine Line Etching

      3 citations , May 2011 in “Facial plastic surgery clinics of North America”
      This article reviews the causes and treatments of fine rhytids, highlighting the potential effectiveness of laser rejuvenation therapies but presents no new clinical results.

      research Periorbital rejuvenation

      1 citations , October 2018 in “Operative techniques in otolaryngology--head and neck surgery”
      This article reviews both minimally invasive and surgical procedures used to treat periorbital aging, highlighting advancements in rejuvenation techniques for areas like the eyebrows and eyelids.

      research Periorbital facial rejuvenation; applied anatomy and pre-operative assessment

      36 citations , April 2017 in “journal of current ophthalmology”
      This review highlights essential preoperative assessments for ophthalmologists and non-oculo-facial surgeons performing upper facial rejuvenation, emphasizing the importance of understanding ocular and periocular anatomy to achieve both cosmetic and functional improvements.