TLDR Negative pressure fractional microneedle radiofrequency effectively and safely reduces periorbital aging signs.
This study assessed the efficacy and safety of negative pressure fractional microneedle radiofrequency (NPFMR) for periorbital aging in 25 patients, with 22 completing it. After two treatment sessions, significant improvements were observed in periorbital wrinkles, skin gloss, and dermal thickness at 6 months post-treatment. There was a decrease in wrinkle count and transepidermal water loss, alongside increased hydration and pH levels. Histological analysis showed increased collagen and elastic fiber expression. The treatment was well-tolerated, with minimal adverse effects, including one case of reversible post-inflammatory hyperpigmentation. Despite the small sample size and short follow-up, NPFMR is considered a safe and effective method for reducing signs of periorbital aging, warranting further research.
15 citations
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March 2020 in “Journal of cosmetic dermatology” PRP is effective for improving the appearance around the eyes.
25 citations
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June 2018 in “Clinical and Experimental Dermatology” Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
115 citations
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April 2010 in “Archives of Dermatology” Surgical face-lifts are more effective, but fractional radiofrequency is a good, less invasive alternative for treating skin laxity.
1 citations
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August 2024 in “European Journal of Medicinal Chemistry Reports” Cosmetic microneedles are promising for precise treatments but face challenges like skin damage and regulations.
42 citations
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January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
July 2024 in “Periodontology 2000” Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.
92 citations
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June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.
