43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
37 citations,
February 2019 in “Experimental Dermatology” Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
29 citations,
September 2020 in “International Journal of Molecular Sciences” The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
28 citations,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
24 citations,
January 2019 in “Biomaterials Science” The shape of fibrous scaffolds can improve how stem cells help heal skin.
16 citations,
March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
9 citations,
June 2020 in “Cell stem cell” Skinny fat cells help wounds heal faster by releasing fatty acids.
8 citations,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
8 citations,
April 2019 in “ACS Biomaterials Science & Engineering” The new SIS-PEG sponge is a promising material for skin regeneration and hair growth.
7 citations,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
5 citations,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
4 citations,
January 2017 in “PubMed” Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.
3 citations,
July 2022 in “Stem Cell Research & Therapy” Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.
November 2023 in “Linköping University medical dissertations” Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
July 2023 in “Stem Cells Translational Medicine” Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
August 2022 in “Biomedicines” Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.
Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
Silk sericin dressing with collagen heals wounds faster and improves scar quality better than Bactigras.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
132 citations,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
110 citations,
April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.
79 citations,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
14 citations,
April 2017 in “American Journal of Transplantation” Skin problems from transplant drugs are common and need careful management in organ transplant patients.