9 citations
,
June 2024 in “BMC Genomics” This study identified genetic variations associated with black and white wool color in Gangba sheep, enhancing understanding of wool color genetics and aiding selective breeding for specific wool colors in Tibetan sheep.
9 citations
,
November 2022 in “Biology” This study identified key genes and pathways related to wool follicle development in coarse wool lambs, suggesting epigenetic factors may influence wool sheep domestication and breeding.
8 citations
,
July 2011 in “Animal science journal” The researchers reported that keratin 33A is a structural protein specific to goat cashmere hair, with increased winter expression in high-cashmere-producing breeds.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
7 citations
,
August 2006 in “Biopolymers” This study demonstrated that human hair shafts can be anatomically separated to obtain intact micron and nano keratin filaments using solvents like performic acid and urea.
7 citations
,
February 1985 in “Textile Research Journal” This study found that wool fiber surfaces damaged in processing tended to have cellular debris adhering to them, while undamaged surfaces did not show this interaction.
6 citations
,
October 2018 in “Endocrinology” This study indicates that sheep prenatally androgenized with testosterone show wool fiber diameter changes that parallel the increased hair diameter in women with polycystic ovary syndrome.
5 citations
,
January 1988 Only two of the four keratin genes are expressed in wool fibers.
2 citations
,
February 2025 in “PLoS ONE” This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.
2 citations
,
December 2019 in “Textile Research Journal” This study found that L-cystine-modified rabbit hair fibers had improved dye adsorption and spinnability, due to changes in secondary structure and surface characteristics.
1 citations
,
March 2017 in “Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego” In this study, researchers observed that underhairs in domestic cats were the thinnest and shortest with regular scales, while guard hairs were the longest and thickest, having irregular scales.
In this study, researchers found two non-synonymous SNPs in the TERT gene associated with mean wool staple strength in sheep, suggesting TERT as a potential candidate gene for improving wool traits.
19 citations
,
January 2009 in “International review of cell and molecular biology” This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.
45 citations
,
January 1986 September 2025 in “Animals” This study analyzed circular RNA expression in the developing skin of foetal Gansu Alpine fine-wool sheep, identifying key circRNAs potentially involved in secondary follicle development through regulatory networks, providing insights for wool trait improvement.
51 citations
,
September 2012 in “Biomacromolecules” This study found that disulfide bonds in keratin increase its strength and toughness, with some loss of α-helical structure under load, highlighting their role in trichocyte α-keratin's mechanical properties.
35 citations
,
November 1931 in “Journal of Genetics” Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.
23 citations
,
November 2014 in “Anais Brasileiros de Dermatologia” This study suggests that trichoscopy may assist in diagnosing pemphigus, particularly for scalp-specific lesions, by identifying certain characteristic features.
19 citations
,
June 2020 in “Animals” This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.
14 citations
,
March 1995 in “Journal of cell science” This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.
12 citations
,
August 1984 in “Genetics Research” In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.
11 citations
,
February 2019 in “Frontiers in Physiology” This review explores the complex interrelationships among different properties of natural hair fibers and underscores the need for a holistic taxonomy to improve data interpretation across disciplines, but it reports no new experimental results.
2 citations
,
July 2023 in “Cosmetics” In this study, researchers highlighted that while hair lipids are crucial for hair health and protection, surfactants in shampoos and conditioners can partially remove these lipids, potentially affecting hair structure, though the exact mechanisms remain poorly understood and require further investigation.
1 citations
,
September 2024 in “Animals” In this study, researchers identified six unique genetic variants of a sheep gene, KRTAP19-3, with specific variants linked to changes in wool fibre traits, such as increased fibre diameter variability, suggesting these genetic differences affect wool characteristics in Chinese Tan sheep.
1 citations
,
August 2021 in “Frontiers in Genetics” This study suggests that melatonin may enhance wool growth in cashmere goats by activating sulfur metabolism genes and high-sulfur protein genes, which are crucial for providing sulfur-containing amino acids needed for wool quality.
This study in Gansu alpine fine-wool sheep identified two SNPs in the KRT71 gene that significantly affect wool length, with distinct expression patterns observed in hair follicles, suggesting KRT71 as a candidate gene for enhancing wool production traits.
January 2013 in “Wageningen Academic Publishers eBooks” This study explored proteomics to investigate protein changes during protein synthesis and keratinization in maturing wool fiber, but the relationship to fibre development remains largely unknown.
10 citations
,
November 2024 in “Animals” This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.
This study analyzed the genetic variations of the KAP20-1 gene in Chinese Tan sheep lambs and found that the G variant was linked to an increased mean fibre curvature in their fine wool fibres, potentially influencing breeding strategies for this wool trait.
This study found that expression and variants of the KRT84 gene are associated with important wool traits in Gansu Alpine Fine-wool sheep, suggesting its potential use as a genetic marker for wool trait selection.