The Proteomics Of Wool Follicles

The study aimed to explore the potential of proteomics in understanding protein changes during the stages of protein synthesis and keratinisation in maturing wool fibers. It was based on previous findings that both sheep and human hair follicles exhibit a sequential pattern in the expression of major keratin and keratin-associated proteins. However, the relationship between expression sequence, post-translational changes, and fiber development was largely unknown at the time. The research sought to provide insights into these processes, contributing to the broader understanding of wool fiber development.