TLDR Proteomics helps understand protein changes in wool fiber development.
The study aimed to explore the potential of proteomics in understanding protein changes during the stages of protein synthesis and keratinisation in maturing wool fibers. It was based on previous findings that both sheep and human hair follicles exhibit a sequential pattern in the expression of major keratin and keratin-associated proteins. However, the relationship between expression sequence, post-translational changes, and fiber development was largely unknown at the time. The research sought to provide insights into these processes, contributing to the broader understanding of wool fiber development.
95 citations
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March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
276 citations
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January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
252 citations
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January 1991 in “Electron Microscopy Reviews”
50 citations
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July 2008 in “British Journal of Dermatology” 138 citations
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March 2007 in “Experimental cell research” Only a few hair-specific keratins are linked to inherited hair disorders.
276 citations
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January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
199 citations
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January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
29 citations
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April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
