The Value of Trichoscopy in the Differential Diagnosis of Scalp Lesions in Pemphigus Vulgaris and Pemphigus Foliaceus

    December 2014 in “ Anais Brasileiros de Dermatologia ”
    Marta Sar‐Pomian, Marta Kurzeja, Lidia Rudnicka, Małgorzata Olszewska
    Image of study
    TLDR Trichoscopy helps tell apart scalp lesions in pemphigus vulgaris and pemphigus foliaceus and is useful for choosing biopsy locations.
    The study, supported by a research grant from the National Science Centre in Poland, investigated the effectiveness of trichoscopy in distinguishing between pemphigus vulgaris (PV) and pemphigus foliaceus (PF) in scalp lesions. It involved 19 patients (9 with PV and 10 with PF) whose diagnoses were confirmed by histopathology. Trichoscopy revealed that extravasations were present in 94.7% of cases, yellow hemorrhagic crusts in 57.9%, and white polygonal structures exclusively in PF (60%). Vascular abnormalities, particularly linear serpentine vessels, were more common in PV (77.8%) than in PF (30%) and were associated with a severe disease course. The study introduced the "fried egg sign," a feature specific to pemphigus, and found that yellow dots with a whitish halo were more frequent in PV (77.8%) than in PF (40%). The study concluded that trichoscopy is a useful supplementary diagnostic tool for pemphigus, especially for selecting biopsy sites, although immunological examinations remain the gold standard for diagnosis.
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results

    Related Community Posts Join

    6 / 70 results

      community 13 days on Ru58841 hair trichoscopy

      in Update  17 upvotes 7 months ago
      The user noticed potential hair growth after 13 days of using RU58841, alongside a regimen of oral minoxidil, finasteride, and topical minoxidil. Others think it's too soon to see results, and some are surprised by the high dosage of oral minoxidil.

      community Predicting Your Hair Loss with a Trichoscopy Report

      in Treatment  7 upvotes 1 year ago
      The conversation discusses the use of trichoscopy to predict hair loss patterns and inform treatment approaches. Treatments mentioned include minoxidil, finasteride, and dutasteride, with varying effectiveness based on gender-specific hair loss patterns.

      community 21m, 2.5 months on 1mg dut & 2.5mg min

      in Progress Pictures  10 upvotes 1 month ago
      A 21-year-old male has been using dutasteride, minoxidil, ketoconazole shampoo, and microneedling for hair loss, with plans to increase minoxidil dosage. He is experiencing no side effects and is planning a trichoscopy to assess hair regrowth.

      community 5+ years on meds, still losing

      in Progress Pictures 2 weeks ago
      The user has been on finasteride and minoxidil since 2020 and increased dutasteride and minoxidil doses in June 2024, but still experiences hair loss. Despite trying pyrilutamide without success, opinions vary on whether the hair loss is significant, with some suggesting it might be due to lighting, angles, or a regular shedding cycle.

      community New Hair Loss Treatment: Adipose Derived Secretomes

      in Research/Science  18 upvotes 6 months ago
      Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

    Related Research

    2 / 2 results