The Value of Trichoscopy in the Differential Diagnosis of Scalp Lesions in Pemphigus Vulgaris and Pemphigus Foliaceus

    November 2014 in “ Anais Brasileiros de Dermatologia ”
    Marta Sar‐Pomian, Marta Kurzeja, Lidia Rudnicka, Małgorzata Olszewska
    Image
    Studysummary This study suggests that trichoscopy may assist in diagnosing pemphigus, particularly for scalp-specific lesions, by identifying certain characteristic features. Our plain-language summary of this paper — not a Tressless recommendation.
    The study, supported by a research grant from the National Science Centre in Poland, investigated the effectiveness of trichoscopy in distinguishing between pemphigus vulgaris (PV) and pemphigus foliaceus (PF) in scalp lesions. It involved 19 patients (9 with PV and 10 with PF) whose diagnoses were confirmed by histopathology. Trichoscopy revealed that extravasations were present in 94.7% of cases, yellow hemorrhagic crusts in 57.9%, and white polygonal structures exclusively in PF (60%). Vascular abnormalities, particularly linear serpentine vessels, were more common in PV (77.8%) than in PF (30%) and were associated with a severe disease course. The study introduced the "fried egg sign," a feature specific to pemphigus, and found that yellow dots with a whitish halo were more frequent in PV (77.8%) than in PF (40%). The study concluded that trichoscopy is a useful supplementary diagnostic tool for pemphigus, especially for selecting biopsy sites, although immunological examinations remain the gold standard for diagnosis.
    Discuss this study in the Community →

    Research cited in this study

    13 / 13 results