1 citations
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April 2025 in “Animals” In this study, nucleotide sequence variation in the KRTAP13-3 gene was associated with changes in heterotypic hair fibre diameter variation in Chinese Tan sheep.
This study investigated the expression of KRTAP6 gene family in Gansu Alpine fine-wool sheep, finding significant expression during the anagen phase and a negative correlation between KRTAP6-1 and KRTAP6-5 expressions with wool fiber diameter and strength.
42 citations
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February 2017 in “Scientific Reports” In this study, researchers differentiated induced pluripotent stem cells into cells with dermal papilla-like properties, demonstrating their potential role in hair follicle bioengineering and drug testing for hair growth.
25 citations
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April 2015 in “Journal of Investigative Dermatology” This study found that Gsdma3 mutation in mice allows hair follicles to bypass a typical telogen phase and directly enter the anagen phase, suggesting Gsdma3's role in hair cycle transitions by regulating Wnt signaling.
19 citations
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January 2023 in “Genes” This study identified genomic regions and genes associated with wool, live weight, body condition, and reproduction traits in Uruguayan Merino sheep, highlighting potential genetic factors influencing these characteristics.
12 citations
,
October 1954 in “Textile Research Journal” This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.
9 citations
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June 2024 in “Genes” This study examined the Spanish Merino breed's wool quality, identifying 74 genetic variants linked to key wool traits like fiber diameter and staple length, which could help restore the breed's potential for producing high-quality wool.
8 citations
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April 2017 in “Journal of The Royal Society Interface” This study found that keratin intermediate filaments in the hair of GAN patients are altered, showing decreased diffraction signals and increased stiffness, strength, and extensibility.
7 citations
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May 2022 in “PLOS ONE” This study found that Hetian sheep with higher wool density produce more and finer wool, with key genes potentially influencing their wool growth and density.
7 citations
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January 1988 6 citations
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October 1988 in “Clinics in Dermatology” This article reviews gaps in our understanding of molecular events in hair follicle growth, focusing on keratin synthesis and protein oxidation, but reports no new findings.
4 citations
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January 2020 in “Genes” This study found that genetic variation in the KRTAP21-2 gene among crossbred Merino lambs was associated with differences in wool traits, particularly mean staple length.
3 citations
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December 2024 in “Journal of Animal Physiology and Animal Nutrition” In this study, researchers found that reducing FGF20 expression in dermal papilla cells of fine-wool sheep impedes the growth and differentiation of hair follicle stem cells, providing insights into wool trait improvement and regenerative medicine applications.
3 citations
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October 2024 in “Animals” This study identified three genes in the ovine KAP13 family on chromosome 1 and found that a specific allele of KRTAP13-2 is associated with improved wool fibre diameter uniformity in Chinese Tan sheep, suggesting its potential use as a marker for enhancing wool traits.
3 citations
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January 1994 1 citations
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January 2024 in “International journal of molecular sciences” This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.
1 citations
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January 2023 in “Frontiers in genetics” This study identified specific genetic markers related to wool quality in Rambouillet sheep, which may aid breeders in making informed selection and breeding decisions for improved fine wool production.
1 citations
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January 2019 in “Studia Biologica” This review discusses the properties and extraction methods of keratins from natural fibers and highlights their promising applications in fields such as biomedicine, bioengineering, and forensic science, but reports no new experimental results.
March 2026 in “Cosmetics” In this comprehensive review, researchers reported that macromolecules like type I collagen, keratin, and ceramides enhance hair health by improving follicular function and increasing hair density, strength, shine, and resilience, as shown in various in vitro, animal, and human studies.
January 2023 in “Kafkas üniversitesi veteriner fakültesi dergisi/Kafkas üniversitesi veteriner fakültesi dergisi” In this study of Angora goats, researchers found that HOXC13 and other genes were overexpressed during the active hair growth phase, suggesting a role in mohair structure.
4 citations
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May 2024 in “Genes” Among Merino × Southdown cross sheep, this study found that certain variants of the KRT81 gene were associated with differences in fleece weight, but not with staple length or fibre diameter traits.
3 citations
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October 2024 in “Animals” In this proteomic analysis, the researchers found that transitioning from crimped to straight wool in Tan sheep is linked to significant changes in wool protein expression, revealing distinct patterns of keratins and keratin-associated proteins that could influence wool quality and economic value.
September 2025 in “Animals” In this study, researchers using Astral—DIA proteomics technology identified 67 differentially expressed proteins in Gansu alpine fine-wool sheep, linking proteins like keratin and MGST3 in pathways to wool fineness regulation, particularly highlighting their association with hair follicle development.
50 citations
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January 1986 46 citations
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August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
39 citations
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January 2020 in “Frontiers in Genetics” This study found that stage-specific epigenetic changes, particularly involving the gene PDGFC, may affect wool fiber development in Zhongwei goats, potentially serving as a biomarker for fur goat selection.
8 citations
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December 2017 in “Small Ruminant Research” This study reports that variation in the ovine TCHH gene may influence wool fibre curvature, with specific gene variants affecting the mean fibre curvature in sheep.
5 citations
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November 2022 in “Genetics selection evolution” This study found that low-coverage whole-genome sequencing followed by imputation effectively identifies genetic variants associated with wool traits in Angora rabbits, offering a cost-efficient method for genetic research and breeding.
3 citations
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March 2023 in “Biology” This study identified 2574 differentially expressed genes in the hair follicles of Wan strain Angora rabbits, suggesting that these genes may influence wool fiber diameter and quality.
2 citations
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May 2023 in “Journal of Advanced Research” In this study, researchers identified two genetic mutations associated with producing finer and denser wool in fine-wool sheep, involving the genes KRT74 and EDAR, which may guide future breeding efforts to enhance wool quality.