2 citations
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January 1987 in “PubMed” This study reported three related cases of woolly hair syndrome transmitted as a dominant autosomal trait, characterized by fine, frizzy hair and general hair thinning.
April 2023 in “Research Square (Research Square)” This study found that melatonin-mediated lncRNA018392 accelerated cell proliferation and inhibited apoptosis in cashmere goat skin fibroblasts by upregulating the expression of the nearby gene CSF1R.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a potent Wnt surrogate with high specificity for the Fzd7 receptor in mice, promoting full hair follicle regeneration and robust hair growth, suggesting potential applications in tissue development and targeted regeneration.
September 2011 in “대한미용학회지” In this study, topical application of 5% bear oil on C57BL/6 mice accelerated hair regrowth and increased hair follicle depth and size more than 2% bear oil, minoxidil, or ethanol.
7 citations
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August 2025 in “Plants” This review highlights the role of plant-derived organic selenium compounds, noting their high bioavailability and low toxicity, and provides a comprehensive overview of selenium's uptake in plants and metabolism in humans, offering a theoretical basis for future nutritional research.
2 citations
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January 2024 in “Pharmaceuticals” This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.
1 citations
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July 2025 in “Cosmetics” This review highlights the multifunctional benefits of plant-derived ingredients in skincare, such as antioxidant and anti-inflammatory effects, supported by biological evidence from medicinal plants like Camellia sinensis and Panax ginseng, suggesting their potential as natural dermocosmetic agents.
March 2026 in “International Journal of Molecular Sciences” This review found that different monosaccharide compositions in polysaccharides from 72 medicinal plants are linked to varying biological activities, with glucans, galactans, mannans, fructans, and pectins showing significant roles in immunomodulation, antioxidant effects, and other health benefits.
November 2025 in “Preprints.org” This review reports that the monosaccharide composition of polysaccharides significantly impacts their bioactivity, highlighting various roles for glucans, galactans, mannans, fructans, and pectin in immune regulation, antioxidant effects, and other biological functions.
June 2024 in “Current Developments in Nutrition” In this study, hydrolyzed keratin supplementation using KeraGLO® significantly improved skin parameters such as wrinkle depth, smoothness, moisture, and firmness, as well as hair health, in healthy adult females over a 90-day period at both 500mg and 1000mg doses.
September 1973 in “Primates”
February 2024 in “Scientific Reports” The wolves suspected of man-eating in the 1880s likely ate very little human flesh and mostly consumed a diet similar to herbivores and omnivores.
This research explores the use of serial block-face scanning electron microscopy to model the complex architecture of sheep wool fibres, focusing on the role and distribution of para- and ortho-cortical cells in determining wool curliness, though the mechanism remains unclear.
30 citations
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December 2014 in “BMC Genetics” This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.
4 citations
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September 2016 in “World Rabbit Science” This study observed that gene expression differences in Rex rabbits with varying wool densities suggest the involvement of specific genes and signaling pathways, including Shh and Eph, in hair follicle development.
September 2016 in “Medical Sains/Medical sains” In this study, applying water extracts of liquorice at a concentration of 2.5% to male rabbits led to the best rate of hair growth at 2.19 cm over 35 days, while a 5% concentration resulted in the greatest hair weight at 0.12 grams.
March 2024 in “International journal of molecular sciences” In this study on Angora rabbits, researchers identified genetic factors influencing wool fiber diameter by analyzing hair follicle proteins, highlighting keratin family members and other proteins as key contributors to fiber differences between coarse and fine wool.
10 citations
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July 2022 in “Electronic Journal of Biotechnology” This study found that the methylation level of the IGFBP4 promoter is negatively correlated with mRNA expression and may serve as an epigenetic marker for wool fineness in Super Merino sheep.
1 citations
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May 2024 in “Animal Biotechnology” In cashmere goats, this study found that reducing miR-361-5p levels activates secondary hair follicle stem cells by upregulating the FOXM1 gene, which in turn stimulates the Wnt/β-catenin pathway, crucial for cashmere fiber morphogenesis.
110 citations
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September 2017 in “Molecules” This review discusses the phytochemistry, pharmacology, pharmacokinetics, and standardization of Forsythiae Fructus, detailing both unripe and ripe forms, but reports no new clinical results.
April 2006 in “Dermatologic Clinics” This study found that white wax and its extract significantly promoted hair growth in a mouse model of androgenetic alopecia, outperforming finasteride by inhibiting 5α-reductase activity and enhancing cellular proliferation.
1 citations
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September 2020 in “Journal of dermatology” This study identified a novel mutation and confirmed a previous mutation in the LIPH gene in a woman with autosomal recessive woolly hair, expanding the mutation spectrum for this condition.
October 2023 in “Cell & bioscience” This study identified a primitive coarse wool characteristic in Merino sheep that enhances environmental adaptability and fine wool yield without reducing quality, suggesting that epigenetic mechanisms, particularly involving the imprinted Gtl2-miRNAs locus, regulate this advantageous trait.
7 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This review discusses the confusion and misuse of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea, highlighting their plant origins, uses, and toxicities, without providing new clinical results.
April 2016 in “Pharmaciana” This study found that a combination of liquorice and aloe vera extracts, particularly combination 1, resulted in the most optimal hair growth in rabbits over a 28-day period.
December 2025 in “Jurnal Ilmiah Kesehatan (JIKA)” This study found that a 15% concentration of Wilalondahi bark extract gel significantly improved wound healing and reduced inflammation in mice, with wounds completely healed by day 9, demonstrating comparable effectiveness to the positive control.
1 citations
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April 2023 in “International Journal of Molecular Sciences” This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.
4 citations
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January 2014 in “Vegetos” This review discusses various medicinal properties and traditional uses of Ziziphus species in human health, emphasizing their potential for new therapeutic applications but reports no new clinical results.
4 citations
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March 2024 in “Cells” This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.
In this study, researchers developed a multifunctional hydrogel for wound healing, incorporating antibacterial and antioxidant properties that demonstrated significant inflammation reduction and tissue regeneration in animal models, with high antibacterial efficacy against E. coli and S. aureus.