51 citations,
September 2008 in “Journal of Investigative Dermatology” Vitamin D receptor may help protect against UV-induced skin cancer.
48 citations,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.
48 citations,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
46 citations,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
45 citations,
April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
44 citations,
February 2023 in “Cell” Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
42 citations,
January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
42 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
37 citations,
June 2017 in “Journal of Investigative Dermatology” Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.
35 citations,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
35 citations,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
34 citations,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
33 citations,
September 2017 in “Molecules” Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
32 citations,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
32 citations,
May 2015 in “Journal of Investigative Dermatology” Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
31 citations,
May 2015 in “Stem Cell Reports” Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
31 citations,
July 2022 in “Advanced healthcare materials/Advanced Healthcare Materials” A drug-free microneedle patch significantly promotes hair growth and prevents infections.
31 citations,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
30 citations,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
30 citations,
January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
29 citations,
January 2021 in “Journal of Investigative Dermatology” Fat under the skin releases HGF which helps hair grow and gain color.
29 citations,
January 2021 in “Journal of nanobiotechnology” Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
29 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
28 citations,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
28 citations,
March 2014 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” The document concludes that hair curvature can be explained by the growth patterns caused by the shape and separation of cells in the hair follicle and is affected by specific molecular pathways.
28 citations,
August 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Survivin protein is crucial for hair growth and preventing cell death in hair follicles.
27 citations,
April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.