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This study found that Wnt/β‐catenin signaling influences the hair follicle regeneration process by prompting quiescent stem cells to enter the cell cycle and is necessary for maintaining the stem cell pool.

This study found that Hedgehog-driven skin tumorigenesis is dependent on the Wnt/beta-catenin signaling pathway and suggests that targeting Wnt ligands could be a potential therapeutic strategy.

In this study, researchers observed that African spiny mice, Acomys cahirinus, are capable of regenerating skeletal muscle in dermal wound sites, unlike common mice, Mus musculus.

This review summarizes recent findings on how Wnt signaling proteins play crucial roles in the cutaneous wound healing process but reports no new clinical results.

This study found that Wnt1a overexpression from bone marrow mesenchymal stem cells enhanced hair follicle regeneration in mice by promoting the dermal papilla's role in hair cycling and gene expression recovery.

This study developed a potent Wnt surrogate with high specificity for the Fzd7 receptor in mice, promoting full hair follicle regeneration and robust hair growth, suggesting potential applications in tissue development and targeted regeneration.

This study suggests that intercellular communication via the WNT5A and STAT pathways may partly drive EMT-like phenomena in keloid pathogenesis, based on findings in an animal model.

This study demonstrated that a combination of four types of honey significantly improved hair integrity, porosity, and surface roughness after exposure to UV-A and pollution stress.

This study found that maintaining a low level of Wnt/β-catenin activity is crucial for mammary gland development, as excessive activity inhibits branching and promotes characteristics of hair follicles instead, highlighting its role in skin appendage identity decisions.

In this study, researchers found that a subset of mammary cells with active Wnt signaling in mice does not develop tumors upon ErbB2 activation and instead undergoes apoptosis, potentially protecting against carcinogenesis.

This study found that low-level laser stimulation activates the Wnt signaling pathway, promoting hair follicle stem cell regeneration and accelerating wound healing.

This study found that in mice, epidermal Wnt/β-catenin signaling influences adipocyte differentiation and hair growth, suggesting its critical role in synchronizing adipogenesis with the hair growth cycle.

This study identified key genes involved in feather follicle development in Wannan chickens, finding that genes such as LAMC2, COL6A3, and WNT7A are crucial in the regulation processes, potentially aiding molecular breeding programs for improved carcass appearance traits.

This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.

This review discusses the role of the Wnt/β-catenin signaling pathway in wound healing, but it presents no new clinical results.

This study observed that activating Wnt signaling pathways increased the efficiency of reprogramming human fibroblasts into induced pluripotent stem cells compared to untreated cells.

Wnt/β-catenin signaling is crucial for cell fusion in placental development.

This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.

This review discusses genetic factors associated with androgenetic alopecia, particularly the roles of the AR/EDA2R locus and histone deacetylases, but it does not present new clinical results.

In this study, researchers found that interaction between transcription factor EBF1 and gene WNT10A, influenced by a genetic variant, may play a role in hair shaft formation and anagen shortening in male pattern baldness.

This study found that Wnt signaling is crucial for bone regeneration, as inhibiting it drastically reduced bone repair in mice, while constitutive activation delayed regeneration by keeping cells in a proliferative state.

This study found that Wnt ligands secreted by the hair follicle epithelium are crucial for hair follicle regeneration in adults and could inform treatments for hair disorders like alopecia.

This study suggests that crosstalk between Wnt/β-catenin and TGF-β signaling pathways may contribute to the development of androgenetic alopecia.

No link found between new male baldness genes and female hair loss.

This study found that the WIF1 gene may play a crucial role in hair follicle growth and development in Angora rabbits by regulating specific genes and proteins.

Wnt and SHH signals together influence hair follicle cell development, offering insights for hair loss treatment.

This study found that androgen signaling can inhibit Wnt-stimulated growth in prostate basal cell organoids, suggesting a key role in regulating their multipotency.

This study observed that activating the Wnt/β-catenin pathway enhances hair follicle stem cell proliferation and differentiation, promoting hair growth and wound healing, and demonstrated the potential for outer root sheath transplants to aid skin repair, although challenges remain for clinical application.

In this study, miR-218-5p was found to enhance hair shaft growth and positively regulate the Wnt signaling pathway by targeting SFRP2 during skin and hair follicle development.

In this study, researchers found that Wnt4 overexpression increased the thickness of burn wounds by promoting epidermal cell migration and activating the canonical Wnt signaling pathway.