Thermal Extraction of Dipicolinic Acid from Bacterial Spores Using Acidic Buffer Solution

This study investigates the impact of bone marrow mesenchymal stem cell (BM-MSC) overexpression of Wnt1a on hair follicle regeneration in mice. The findings indicate that Wnt-conditioned medium (Wnt-CM) accelerates the transition of hair follicles from the telogen to anagen phase and enhances alkaline phosphatase (ALP) expression in the dermal papilla (DP) area. Additionally, Wnt-CM treatment upregulates hair induction-related genes and restores DP cell gene expression affected by dihydrotestosterone. The study concludes that BM-MSC-generated Wnt1a enhances the DP's capacity to induce hair cycling and regeneration.