Low-Level Laser Activates Wnt/β-Catenin Signaling Pathway Promoting Hair Follicle Stem Cell Regeneration and Wound Healing: Upregulate the Expression of Key Downstream Gene Lef1

    June 2024 in “ Skin Research and Technology
    Banghong Jiang, Yukun Wang, Shi Ao, Tao Sun, Peijun Song, Xuwen Li, Lin Li, Zhuyou Xiong, Zhang Li
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    Studysummary This study found that low-level laser stimulation activates the Wnt signaling pathway, promoting hair follicle stem cell regeneration and accelerating wound healing.
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    The study demonstrates that low-level laser therapy (LLLT) activates the Wnt/β-catenin signaling pathway, which in turn promotes the regeneration of hair follicle stem cells and accelerates wound healing. This process involves the upregulation of the key downstream gene Lef1. The findings suggest that LLLT could be a promising approach for enhancing hair growth and improving wound healing by targeting specific molecular pathways.
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