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This study highlights a treatment approach using dissolving microneedle patches containing nanomicelles formed by stevioside to enhance the therapeutic efficacy and safety of poorly soluble drugs, as depicted in the cover illustration with luxuriant hair symbolizing its potential effectiveness.

This study found that the optimized topical AR antagonist 39, derived from 14-P1, demonstrated potent AR antagonism and comparable efficacy to pyrilutamide in a hair-growth mouse model, with a faster onset and favorable safety profile.

This article reviews current treatments for alopecia areata, discussing the potential role of JAK inhibitors and noting the need for further clinical trials, but it reports no new results.

This study evaluated the antimicrobial activity of Albizia saponaria stem bark against microorganisms causing dandruff and fungal alopecia. It found that the hexane fraction exhibited potent antifungal effects comparable to ketoconazole, highlighting its potential as a natural therapeutic for dandruff.

In this study, a standardized 7.5% herbal extract significantly increased hair growth in men with androgenetic alopecia compared to a placebo over a 48-week period.

In this phase 2 trial, STS01 1% significantly improved hair regrowth in patients with mild to moderate patchy alopecia areata compared to placebo, with a manageable skin irritation side effect profile.

This study suggests that applying a botanical extract targeting mechanosensory receptors improved well-being, oxytocin levels, and skin appearance in participants, unlike a placebo.

In this randomized controlled study, the researchers found that an herbal extract combination showed similar efficacy to 3% minoxidil solution in treating androgenetic alopecia over 24 weeks, with no significant safety concerns, suggesting it might be a viable alternative treatment.

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

This article discusses a proprietary botanical lotion with potential to reverse chemotherapy-induced alopecia, restore hair cycles, and improve patient wellbeing; however, it reports no new clinical results.

This paper reviews the challenges of treating alopecia areata affecting eyelashes and discusses the risks associated with traditional therapies; it reports no new clinical results.

The authors concluded that newly synthesized N-acyl-L-tryptophanyl-isoleucine amides showed high anxiolytic activity in animal models, comparable to diazepam, through interaction with the TSPO receptor.

This study observed that a combination of sinapic acid and glabridin from Zhimo herbal extract improved hair growth and reduced oxidative stress in a DHT-induced model of androgenetic alopecia in mice by preventing ferroptosis and stabilizing β-Catenin, offering potential application for AGA treatment.

This study found that the ethanolic extract of Acanthus ebracteatus demonstrated potential as an anti-hair loss treatment by promoting dermal papilla cell proliferation, inhibiting 5α-reductase activity, and reducing inflammation in vitro.

This study found that a polyherbal formulation of Trigonella foenum-graecum and Butea monosperma significantly promoted hair growth and reduced DHT levels in a chemotherapy-induced alopecia model.

This study found that the water fraction of Panax ginseng may reduce apoptosis and enhance medullary cell formation in the hair follicles of irradiated mice, suggesting a potential protective effect.

This study elucidated the multi-component and multi-target mechanisms by which TR and Am may provide therapeutic benefits for treating androgenetic alopecia.

This study reported that optimized transfersomes and their gel form significantly improved transdermal delivery and hair growth promotion of minoxidil in C57BL/6 mice compared to commercial formulations.

This review discusses the traditional uses of Tridax procumbens for wound healing, antifungal, and antibacterial purposes, but reports no clinical findings.

This study found that the YH0618 decoction reduced chemotherapy-induced nail discoloration, alopecia, skin hyperpigmentation, and fatigue in cancer patients who completed chemotherapy.

In this phase I study, CG2001, a topical foam combining minoxidil and finasteride, was found to be safe and well-tolerated in Chinese males with androgenetic alopecia, showing significantly reduced systemic finasteride exposure compared to oral administration, potentially reducing related side effects.

In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.

This study found that progesterone protects rat Purkinje cells during oxygen-glucose deprivation by activating GABA A receptors through its metabolite, allopregnanolone.

This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.

In this study, gelatin-coated transferosomes were developed to deliver tofacitinib specifically to hair follicles, resulting in 80% hair regrowth in alopecia areata patients with recalcitrant lesions after 12 weeks of treatment.

In this study, the ethanol extract of Zapoteca portoricensis stem significantly reduced markers of testosterone-induced benign prostate hyperplasia in male albino rats without harming liver and kidney function.

This review compiles data on Platycladus orientalis leaves, noting their diverse pharmacological activities and advocating for more research to clarify their traditional blood-cooling and hematostatic uses.

In this study, the researchers reported that women with diffuse telogen alopecia who took Wolvit® (biotin 5 mg) daily for 3 months showed a significant decrease in hair in the telogen phase and an increase in hair thickness and growth speed.

This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.