research Emerging Concepts About Prenatal Genesis, Aberrant Metabolism, and Treatment Paradigms in Polycystic Ovary Syndrome
PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
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research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research JAK Inhibitors in Dermatology: The Promise of a New Drug Class
JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
research Rapid Mechanosensitive Migration and Dispersal of Newly Divided Mesenchymal Cells Aid Their Recruitment into Dermal Condensates
Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
research Efficacy of Tofacitinib in Treatment of Alopecia Universalis in Two Patients
Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.
research Targeting a Fibrotic Bottleneck May Provide an Opening in the Treatment of LUTS
New treatments targeting fibrosis could improve urinary symptoms in BPH.
research Age-Associated Inflammation Inhibits Epidermal Stem Cell Function
Aging causes skin stem cells to work less effectively.
research Complications of Liver Transplantation: A Perioperative Perspective
Liver transplant can lead to neurological, pulmonary, cardiovascular, and renal complications, with older patients facing higher risks.
research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.
research Mucocutaneous Manifestations of Endocrine Disorders
Skin symptoms can indicate endocrine disorders and have various treatments.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Parathyroid Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin
PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
research Montagna Symposium 2017—Precision Dermatology: Next Generation Prevention, Diagnosis, and Treatment
The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.
research Exogenous Testosterone or Testosterone with Finasteride Increases Bone Mineral Density in Older Men with Low Serum Testosterone
Testosterone therapy increases bone density in older men with low testosterone levels.
research A New Species of Aplodontopus (Acari: Astigmata: Chortoglyphidae) from the Yellow-Bellied Marmot, Marmota Flaviventris (Rodentia: Sciuridae) in Eastern Washington, USA, with Observations on Its Pathology
Researchers found a new mite species causing severe hair loss and skin problems in yellow-bellied marmots.
research Are Sex Discordant Outcomes in COVID-19 Related to Sex Hormones?
Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
research Ulcerative Colitis and Total Alopecia in a Mother and Her Son
A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.
research Pharmacokinetics, Toxicity, and Activity of Intravenous Dextran Sulfate in Human Immunodeficiency Virus Infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research Autosomal Recessive Congenital Ichthyosis Due to PNPLA1 Mutation in a Golden Retriever–Poodle Cross-Bred Dog and the Effect of Topical Therapy
Long-term oral and topical treatments improved skin condition in a goldendoodle with a genetic disorder.
research Hormone Replacement Therapy and COVID-19 Outcomes in Solid Organ Transplant Recipients Compared With the General Population
Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.
research Successful Management of Minoxidil Toxicosis in a Dog
A dog fully recovered from minoxidil poisoning after receiving treatment.
research Trichotillomania: Neurobiology And Treatment
Trichotillomania involves hair pulling and can be treated with therapy and medication.
research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men
Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
research Review of Factors Affecting the Growth and Survival of Follicular Grafts
Optimal storage solutions and effective additives are crucial for improving the survival of hair transplant grafts.
research The Logic of Follicular Unit Transplantation
The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.
research Cosmetic Plastic Surgery Trends and Procedures for Male Patients
More men are getting cosmetic surgery, with nose jobs and hair transplants being popular, and choosing a qualified surgeon is important.
research Identifying Long-Term Effects of SARS-CoV-2 and Their Association With Social Determinants of Health in a Cohort of Over One Million COVID-19 Survivors
Long-term effects of COVID-19 can vary over time and are more likely in certain age and gender groups, while race, income, and education levels have little to no impact. Ongoing medical care is needed due to potential complications.
research Thyroid Hormones and Androgens Differentially Regulate Gene Expression in Testes and Ovaries of Sexually Mature Silurana Tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.