July 2023 in “Media Dermato Venereologica Indonesiana” In this study, researchers highlighted that in sarcoidosis, macrophages in granulomas can produce vitamin D, potentially leading to calcium imbalances, where vitamin D supplementation may cause hypercalcemia, necessitating careful laboratory assessment before supplementation.
1 citations
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February 2022 in “Journal of the American Academy of Dermatology” This review discusses biotin supplementation for dermatological conditions and highlights the lack of strong evidence supporting its efficacy, as well as the potential for laboratory testing interference.
5 citations
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July 2018 in “Pediatrics” This case report describes a previously healthy 3-year-old girl who developed scurvy symptoms not directly linked to vitamin C dietary deficiency, highlighting the potential for misdiagnosis in similar cases.
October 2023 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” This article discusses how vitamin D supplementation impacts human aesthetics and health, with effects varying positively or negatively based on different dermatological conditions.
March 2019 in “Evidence Based Women Health Journal (Online)” This study found that vitamin D supplementation increased the cumulative ovulation rate in vitamin D deficient women with polycystic ovary syndrome compared to those with normal vitamin D levels and a control group.
May 2024 in “Journal of ayurveda and integrated medical sciences” In this study, a clinical trial on a vegan patient with Vitamin B12 deficiency showed that administering Amra Beej Majja Churna over two months increased serum Vitamin B12 levels and alleviated symptoms like hair loss and tingling sensations in the lower limbs.
3 citations
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March 2022 in “International Journal of Trichology” This study found that nutritional supplementation with hydrolyzed collagen, amino acids, vitamins, and minerals significantly improved hair anagen/telogen ratios and hair density in telogen effluvium patients.
1 citations
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August 2004 in “Alternative & complementary therapies” Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.
1 citations
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November 2024 in “AME Medical Journal” In this case study, scurvy was diagnosed in a middle-aged man on hemodialysis with food insecurity and undetectable vitamin C levels, highlighting the diverse risk factors and persistent challenges in managing vitamin C deficiency among patients with complex medical and social issues.
76 citations
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April 2002 in “Urology” This review examines the use of selenium and vitamin E supplements for reducing prostate cancer risk, finding mixed evidence that suggests benefits may be limited to individuals with specific risk factors, like low baseline levels or smoking history, rather than broadly applicable.
September 2025 in “Clinics and Practice” This study found that six-month supplementation with fish-derived collagen peptides, calcium, and vitamin D3 improved skin hydration and elasticity and reduced hair loss in menopausal women, with collagen playing a dominant role in enhancing skin elasticity.
July 2025 in “Food Science & Nutrition” This study found that vitamin D supplementation in diets of Rex rabbits improved hair follicle development and fatty acid metabolism, with 1400–2100 IU/kg proving most effective for hair density and 2800 IU/kg increasing hair length.
April 2025 in “Journal of Controversies in Obstetrics & Gynecology and Pediatrics” This study found that vitamin D supplementation significantly improved clinical pregnancy rates in women with polycystic ovary syndrome treated at a Turkish infertility clinic, though it did not affect live birth or miscarriage rates.
This study observed that women with PCOS have a higher likelihood of vitamin D deficiency, particularly if they are obese, compared to women without PCOS.
April 2024 in “The Egyptian Family Medicine Journal/The Egyptian Family Medicine Journal ” This randomized controlled trial found that vitamin D supplementation significantly improved various post-COVID-19 symptoms, such as fatigue and sleep disturbances, compared to placebo over two months, emphasizing the role of vitamin D deficiency in persistent symptoms among post-COVID-19 patients.
September 2022 in “Al-Azhar University Journal of Virus Researches and Studies” This study found that vitamin D supplementation significantly improved ovulation rates in PCOS patients undergoing treatment with clomiphene citrate.
April 2016 in “Journal of The American Academy of Dermatology” A vitamin and mineral supplement significantly reduced hair shedding in Brazilian women with telogen effluvium.
May 2025 in “International Journal of Trichology” In this study, Pilopeptan® Intensive, a nutritional supplement containing hydrolyzed collagen, Group B vitamins, and zinc, was found to significantly improve hair parameters in telogen effluvium patients, with sustained benefits observed posttreatment, although mild side effects were reported by some participants.
January 2025 in “Clinical Pediatric Endocrinology” In a case study of vitamin D-dependent rickets type 2A, researchers observed that while active vitamin D treatment failed to improve bone and laboratory abnormalities, oral calcium lactate significantly ameliorated these issues, although skin and hair problems remained unresponsive.
1 citations
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January 2021 in “Journal of Dermatology and Dermatologic Surgery” This study found that taking Vitamin D supplements may be associated with a higher risk of hyperpigmentation after laser hair removal.
June 2024 in “British Journal of Dermatology” In this case report, an 80-year-old woman experienced darkening of previously grey hair, which may be linked to vitamin B supplementation, though its effectiveness is typically associated with reversing greying only in the presence of an initial vitamin B deficiency.
April 2019 in “Journal of the Endocrine Society” This case report suggests that a supplement containing biotin, beta carotene, vitamin C, zinc, and copper may improve insulin resistance markers and hair loss in a patient with non-classic 11-hydroxylase deficiency.
February 2026 in “Pakistan Veterinary Journal” In this study of White cashmere goat ewes and their offspring in Tibet, selenium and vitamin E supplementation improved antioxidant capacity and serum biochemical indices and enhanced secondary hair follicle development in lambs, but did not significantly alter fecal microbiota composition.
This study reports that their population showed significant prevalence of vitamin D deficiency, but the impact of supplementation on pregnancy rates remains unclear and requires more research.
October 2008 in “Trace Elements and Electrolytes” In this study, perimenopausal women with initially high hair concentrations of calcium, magnesium, and silicon experienced a decrease in these elements after intermittent dietary supplementation with calcium, magnesium, silicon, and vitamin D.
20 citations
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June 2020 in “Journal of Advanced Research” This study found that high-dose vitamin A and E supplementation with zinc may improve glycemic control and beta-cell function in patients with type 2 diabetes, compared to no supplements.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this N=1 case study, a long-term zero-carbohydrate diet adult male experienced an increase in fasting plasma ascorbic acid from 0.1 mg/dL to 2.0 mg/dL within two months of daily 1 g vitamin C supplementation, along with subjective health improvements.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this N=1 case study, researchers observed that a 1 g daily dose of vitamin C successfully elevated plasma vitamin C levels in an adult male following a zero-carbohydrate diet, with reported improvements in some health parameters but no gastrointestinal side effects.
The authors of this study concluded that higher calcium levels in hair may indicate early metabolic changes leading to osteopenia or osteoporosis in menopausal women, even before detectable by standard DEXA imaging.
July 2025 in “Insights-Journal of Health and Rehabilitation” This study found that adding vitamin D supplementation to metformin therapy led to a greater reduction in HbA1c levels compared to metformin alone in patients with type 2 diabetes, suggesting an enhanced improvement in glycemic control.