Comparison of Metformin With Vitamin D Supplementation and Metformin Alone in Terms of Reduction in Level of HbA1c in Patients Diagnosed With Diabetes Mellitus Type II
July 2025
in “
Insights-Journal of Health and Rehabilitation
”
Studysummary This study found that adding vitamin D supplementation to metformin therapy led to a greater reduction in HbA1c levels compared to metformin alone in patients with type 2 diabetes, suggesting an enhanced improvement in glycemic control.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This study compared the effects of metformin combined with vitamin D supplementation versus metformin alone on HbA1c levels in 140 patients with type 2 diabetes mellitus over three months. Group A, receiving both metformin and vitamin D, showed a greater reduction in HbA1c levels (10.1 mmol/mol) compared to Group B, which received only metformin (7.2 mmol/mol). The results indicate that adding vitamin D to metformin therapy significantly improves glycemic control without serious adverse events, suggesting that vitamin D supplementation could be beneficial in diabetes management, especially in areas with high vitamin D deficiency.
