This study observed that women with PCOS have a higher likelihood of vitamin D deficiency, particularly if they are obese, compared to women without PCOS.
10 citations
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February 2017 in “Hormone Molecular Biology and Clinical Investigation” This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.
1 citations
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October 2013 in “Journal of Postgraduate Medical Institute” This study reported that Metformin effectively improved menstrual irregularities, LH:FSH ratio, and serum testosterone in women with PCOS, but did not alleviate hyperandrogenism symptoms.
This study found that metformin significantly improved clinical and hormonal indices in patients with polycystic ovary syndrome compared to pioglitazone, which also effectively controlled some symptoms.
14 citations
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October 2016 in “Physiological Research” In this study, vitamin D supplementation showed no significant effect on androgen levels or clinical hyperandrogenism in PCOS women, but when combined with metformin, it improved testosterone levels.