Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium

May 2025 in “ International Journal of Trichology ”

Eva María Arias, Sara Manzanares, Nuria Floriach, Eduard Sarró, Estela Bravo, Ignacio Querol

telogen effluvium hydrolyzed collagen Group B vitamins zinc nutritional supplement hair thickness hair shedding hair strength hair brightness hair softness pull test Pilopeptan Intensive

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Studysummary In this study, Pilopeptan® Intensive, a nutritional supplement containing hydrolyzed collagen, Group B vitamins, and zinc, was found to significantly improve hair parameters in telogen effluvium patients, with sustained benefits observed posttreatment, although mild side effects were reported by some participants.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study on Pilopeptan® Intensive, involving 343 participants, demonstrated significant improvements in hair parameters such as thickness, amount, shedding, strength, brightness, and softness in individuals with telogen effluvium (TE) over a 1-month treatment period and a subsequent 30-day washout. The supplement, containing hydrolyzed collagen, vitamins B5 and B6, and zinc, was well-tolerated with mild side effects and high adherence. The benefits persisted post-washout, suggesting lasting effects, and participants reported satisfaction with the treatment. While the results are promising, further research, particularly randomized controlled trials, is needed to confirm long-term efficacy and safety. The study was funded by Laboratorio Genove S.A. with no conflicts of interest reported.

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