4 citations
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January 1965 in “THE JOURNAL OF VITAMINOLOGY” In this study, applying 0.5% vitamin E lotions on rabbits accelerated hair growth and increased it up to 2.4 times compared to controls within four weeks.
2 citations
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October 1961 in “Experimental Biology and Medicine” This study found that rabbits fed a diet deficient in Vitamin E developed severe muscular dystrophy that was not fully prevented by adding selenium, Vitamin E supplements, or natural feedstuffs, indicating other nutritional deficiencies.
22 citations
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January 1968 in “THE JOURNAL OF VITAMINOLOGY” This study found that α-tocopheryl acetate is well absorbed through healthy skin, with absorption occurring through specific pathways and showing high affinity for small blood vessels.
7 citations
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December 2020 in “Pharmaceutics” In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.
1 citations
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December 2022 in “Journal of applied biological chemistry” This study found that TRP-hair essence significantly protected and improved the quality of human hair, particularly against heat stress, by enhancing cuticle health and maintaining hair color.
1 citations
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September 2022 in “Journal of dermatological science” This study found that a combination of vitamins in hair care products promoted hair shaft elongation in a mouse model by activating the PlGF/VEGFR-1 signaling pathway.
October 2023 in “International Journal of Pharmaceutics” This study found that ethosome-loaded minoxidil and tocopherol acetate improved hair regeneration and regulated the microenvironment around hair follicles better than commercial minoxidil in androgenic alopecia model mice, showing promise as a treatment strategy.
August 2025 in “İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi” In this study, the researchers developed a chromatographic method to determine α-tocopherol and α-tocopheryl acetate in pharmaceutical capsules with high accuracy and repeatability, establishing it as a reliable alternative for analyzing these compounds.
September 2018 in “Reactions Weekly” Two women had skin reactions from a hair loss treatment and got better after stopping use.
5 citations
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February 1992 in “Journal of chromatography A/Journal of chromatography” This study developed a rapid, precise, and specific chromatographic method to measure alpha-tocopheryl nicotinate in cosmetics, using alpha-tocopheryl acetate as an internal standard.
December 2021 in “Journal of Applied Biological Chemistry” This study observed that toothpaste and its active constituents promoted hair growth in mice, suggesting their potential for hair growth applications.
February 2022 in “Scientia Pharmaceutica” This study validated that six out of seven tested topical formulations for alopecia are compatible for 6-month use, suggesting they may be practical for compounding pharmacies.
18 citations
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October 1986 in “PubMed” This study found that alpha-tocopherol acetate did not demonstrate any protective effect against hair loss induced by doxorubicin in patients with solid tumors.
30 citations
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December 2019 in “PLoS ONE” This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.
11 citations
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August 1997 in “Expert Opinion on Therapeutic Patents” This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.
2 citations
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July 1982 in “British Journal of Dermatology” This study reports that retinol acetate inhibited the pro-oxidant effects of benoxaprofen on polymorphonuclear leucocytes in vitro.
2 citations
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September 2023 in “Scientific reports” This study reports that zinc oxide or silver nanoparticles capped with vitamin A or E, incorporated into wheat gluten films, showed significant potential in promoting burn wound healing in mice by facilitating wound contraction, re-epithelialization, and collagen deposition, while also exhibiting antioxidant and antibacterial properties.
June 2021 in “International journal of cosmetics and dermatology” This review found limited support for oral vitamin C and E in treating pigmentary disorders like chloasma, inflammatory conditions, and pressure wounds, with evidence constrained by small, varied studies.
January 1982 in “Side effects of drugs annual” This review discusses the therapeutic effects of vitamins, highlighting risks such as liver damage from prolonged high doses of vitamin A and hypercalcemia from excessive vitamin D, while noting a case of allergic reaction to vitamin B12.
36 citations
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May 2017 in “The journal of sexual medicine” In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.
83 citations
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April 1992 in “Clinical Endocrinology” This study found that treatment with cyproterone acetate and ethinyl oestradiol increased hair density in women with diffuse androgen-dependent alopecia, particularly when serum ferritin levels were above 40 μg/l.
27 citations
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October 1945 in “Endocrinology” In this study, adrenalectomy in black rats on a vitamin B-deficient diet restored hair growth and melanin deposition, effects reversed using adrenal cortical hormones.
January 2025 in “Global Health” This study found that Bangladeshi patients with type 2 diabetes mellitus had significantly lower serum vitamin E levels compared to healthy individuals, with lower levels particularly observed in female and older patients, emphasizing the potential importance of antioxidant status in managing the disease.
This review found that various treatments like finasteride, minoxidil, and platelet-rich plasma, combined with supplements, showed positive responses in combating androgenetic alopecia. The study specifically highlighted finasteride's effectiveness in increasing hair growth, with different dosages yielding notable improvements in both men and pre-menopausal women.
December 2023 in “Asian journal of beauty & cosmetology”
12 citations
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December 1987 in “Cancer Chemotherapy and Pharmacology” Vitamin E in the diet might help protect against hair loss caused by the chemotherapy drug doxorubicin in rabbits.
24 citations
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June 2010 in “Clinics in Dermatology” This review discusses various potential adverse effects of common oral vitamin and mineral supplements used in dermatology and highlights lesser-known issues like hematologic and neurologic effects from zinc.
1 citations
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January 2013 in “Springer eBooks” Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
6 citations
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May 2011 in “Pharmacognosy Journal” This review discusses the causes of alopecia, including androgenetic alopecia, and potential active ingredients for hair regrowth, but it does not report new clinical results.
December 2025 in “International Journal of Pharmaceutical Sciences Review and Research” In this study, a newly developed polyherbal hair oil exhibited promising characteristics, including a beneficial pH and antimicrobial activity against Staphylococcus aureus, with preliminary tests suggesting it supports scalp and hair health without adverse effects.