Adverse Reactions to Ethinylestradiol, Salicylic Acid, Swertia Japonica, and Tocopherol Acetate in Female Pattern Hair Loss Treatment

September 2018 in “ Reactions Weekly ”

ethinylestradiol salicylic acid swertia japonica tocopherol acetate female pattern hair loss FPHL erythema topical solution vitamin E topical treatment

TLDR Two women had skin reactions from a hair loss treatment and got better after stopping use.

The document reports on a study involving two women, aged 40 and 64, who experienced adverse reactions while using a topical solution containing ethinylestradiol/salicylic acid/swertia japonica/tocopherol acetate for the treatment of female pattern hair loss (FPHL). The 40-year-old developed mild itching after 13 weeks, and the 64-year-old developed moderate erythema after 12 weeks of twice-daily application. Both women ceased using the product as a result, and their symptoms resolved upon discontinuation. The study highlights the occurrence of adverse reactions in these two patients during the treatment.

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