December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This preprint reports meaningful improvements in hair density and scalp coverage in an elderly female with androgenetic alopecia treated through an integrative regenerative protocol, involving microneedling and plant-derived exosomes, among other non-pharmacological interventions focusing on cellular senescence pathways.
110 citations
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November 1984 in “The American Journal of Medicine” This study observed that children with a genetically transmitted defect in the 1,25-dihydroxyvitamin D3 receptor experienced spontaneous healing of rickets as they aged, despite persistent mineral imbalances during treatment.
10 citations
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August 2021 in “Journal of Cosmetic Dermatology” This study retrospectively analyzed 3028 patients with telogen effluvium, finding that 6.2% had iron deficiency anemia and vitamin D deficiency was common, especially in women who were more often prescribed vitamin D therapy.
5 citations
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September 2021 in “Journal of cosmetic dermatology” This study found that alopecia areata patients had significantly abnormal T3, T4, TPOAbs, ANA, and lower vitamin D levels compared to healthy controls.
1 citations
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January 2011 Thorough evaluation and lab tests are crucial for understanding hair loss causes.
January 2024 in “Veterinary Science and Medicine Journal” This case study reported successful treatment of ankylostomyosis and scabiosis in a three-month-old cat using ivermectin and pyrantel pamoate, improving symptoms significantly after three weeks.
July 2023 in “Dermatology practical & conceptual” In this study, hemoglobin levels were the only marker positively correlated with anagen hair ratios in patients with telogen effluvium, suggesting it may be a cost-effective initial test for management.
June 2023 in “JAAD international” This report highlights that 49.4% of U.S. patients with skin issues use complementary and alternative medicine (CAM), with 6% leveraging it specifically for their skin conditions, including treatments like herbal, vitamin, and mineral supplementation for alopecia.
August 2022 in “Journal of the American Academy of Dermatology” This review discusses the risk factors, clinical presentation, diagnosis, and management of dermatoses linked to B-complex vitamin deficiencies, including biotin, but does not address risks from over-supplementation.
January 2013 in “Российский журнал кожных и венерических болезней” This study found that intradermal injections of group B vitamins and cystin B6 complex improved scalp circulation, supported hair growth, and reduced hair loss in patients with diffuse alopecia.
138 citations
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June 2004 in “Journal of Investigative Dermatology” This review discusses the regulation of involucrin gene expression, focusing on transcription factors and signaling pathways, and reports no new experimental findings.
71 citations
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October 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study highlights the complex role of the vitamin D receptor in skin processes, where its disruption, along with calcium and co-regulator imbalances, could contribute to skin cancer development by altering skin differentiation and hair follicle cycling.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study investigated the effects of a recombinant human collagen complex on hair growth, finding it enhanced survival and function of hair follicle stem cells and promoted hair growth in rat models, suggesting its potential for hair loss prevention and hair health maintenance.
September 2019 in “Ukrainian Journal of Dermatology Venerology Cosmetology” In this study, 90 pediatric patients with scalp microsporia were treated with a combination of griseofulvin, Antral, sertaconazole nitrate cream, and Bion 3 Kid, resulting in complete recovery, reduced treatment duration, and prevention of disease recurrence and colds, with high drug tolerability.
January 2013 in “Российский журнал кожных и венерических болезней” This article reviews the pathophysiology and limited effectiveness of current treatments for androgenic alopecia, including finasteride, minoxidil, botulinum toxin A, and platelet-rich plasma, and highlights the need for new therapeutic approaches; it reports no new clinical findings.
April 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This case study reported significant improvement in autoimmune-related symptoms, including complete hair regrowth, in a patient with systemic lupus erythematosus and alopecia areata after treatment with the LGS Protocol.
Men need essential vitamins like D, B Complex, and A for health, and should consult doctors for personalized advice.
1308 citations
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March 1998 in “Journal of bone and mineral research” This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.
18 citations
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October 2009 in “Endocrinology” This study demonstrated that both HR isoforms are expressed in keratinocytes, but HRDelta1072-1126 lacks corepressor activity and may act as a coactivator by inhibiting HDAC recruitment to the VDR transcriptional complex.
4 citations
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May 2021 in “Molecules” This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.
2 citations
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May 2018 in “Journal of the American Academy of Dermatology” This meta-regression analysis observed a slightly negative but nonsignificant correlation between vitamin D levels and the severity of alopecia areata, suggesting a complex relationship that requires further investigation.
1 citations
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November 2024 in “AME Medical Journal” In this case study, scurvy was diagnosed in a middle-aged man on hemodialysis with food insecurity and undetectable vitamin C levels, highlighting the diverse risk factors and persistent challenges in managing vitamin C deficiency among patients with complex medical and social issues.
5 citations
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January 1998 in “Journal of dermatological treatment” This study found that calcitriol, tacalcitol, and calcipotriol ointments achieved complete clearance of scalp psoriasis in 45%, 35.2%, and 17.6% of patients, respectively, with minimal side effects.
1 citations
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January 2018 in “Journal of Steroids & Hormonal Science” This study observed no significant difference in vitamin D levels between children with alopecia areata and controls, but higher complete improvement in alopecia was noted among patients with vitamin D deficiency undergoing oral vitamin D treatment.
52 citations
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August 1993 in “Clinical endocrinology” This study found that intravenous high dose calcium infusions followed by high dose oral calcium effectively treated vitamin D dependent rickets type II, leading to complete biochemical and radiological healing and improved growth in two patients.
1 citations
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August 2004 in “Alternative & complementary therapies” Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.
13 citations
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October 2019 in “Oncology Reports” This review discusses the complex relationship between anabolic substances and colorectal cancer risk, reporting ambiguous findings on their carcinogenic properties, potential synergy with risk factors, and protective roles.
146 citations
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January 2004 in “Hormones” This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.
54 citations
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March 2009 in “BioEssays” This review discusses the complex hormonal control of keratin expression in skin and its potential implications for treating skin and hair disorders, but reports no new clinical results.
2 citations
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February 2016 in “Vestnik dermatologii i venerologii” This study found that complex therapy including biomimetic peptides was effective in treating alopecia compared to a similar treatment without the peptides.