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Fat cells in the skin help start healing and form important repair cells after injury.

Testosterone may slow down wound healing and increase inflammation.

Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Injecting triamcinolone acetonide near surgical cuts doesn't greatly affect wound healing but may help in areas with less tension.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Minoxidil effectively lowers blood pressure with few side effects.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

CD98hc's role in skin health decreases with age.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.