December 2025 in “Pharmaceutics” This review highlights the potential of drug-loaded extracellular vesicles as a promising drug delivery platform but notes that clinical translation faces challenges due to variability in methods and the need for standardization and safety evaluation.
3 citations
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January 2000 in “Current Medical Research and Opinion” This research reported that eflornithine HCl 13.9% cream generally has a favorable dermal safety profile for managing unwanted facial hair in women, though it can cause mild irritation under certain conditions.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.
In this study, VB-1 was reported to promote human hair follicle growth by enhancing Wnt/β-catenin signaling and increasing human dermal papilla cell proliferation in vitro.
6 citations
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April 2025 in “Frontiers in Sustainable Food Systems” This review highlights the potential of valorizing vegetable waste by extracting valuable biomolecules for use in food, nutraceuticals, and energy, noting that while promising methods exist, several niche areas lack sufficient research on a global scale.
February 2020 in “Jurnal pendidikan dan keluarga/Jurnal Pendidikan dan Keluarga” In this quasi-experimental study, using avocados and VCO for hair loss treatment did not significantly differ among experimental groups, but showed significant improvement compared to the control group in reducing the amount of hair loss.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This document promotes an Erthwellness discount code that offers a 25% reduction on all their natural health products, without presenting any new research findings.
December 2023 in “Asian journal of beauty & cosmetology” 4 citations
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April 2025 in “Frontiers in Immunology” This article discusses the potential of extracellular vesicles for developing precise psychiatric therapies and the need for interdisciplinary collaboration, but reports no new clinical results.
June 2026 in “Advanced Healthcare Materials” This study found that engineered extracellular vesicles (293F-EGF-EV), enriched in EGF mRNA, significantly aided skin wound healing in vitro and in a rat model by promoting fibroblast activity and improving wound recovery through processes like angiogenesis and reduced scarring.
1 citations
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February 2024 in “Cosmetics” In this review, researchers explored the potential of cannabinoids, particularly cannabidiol, as a holistic treatment for acne vulgaris, highlighting their lipostatic, anti-inflammatory, antiproliferative, and antimicrobial effects in modulating acne-related factors like sebum production and inflammation.
88 citations
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May 2024 in “Journal of Extracellular Vesicles” This scoping review found that while some small human pilot trials of extracellular vesicles as therapeutics showed promising outcomes, variability in study design and lack of placebo controls limit definitive conclusions about their safety and efficacy.
September 2025 in “Frontiers in Pharmacology” This study suggests that P. orientalis leaf-derived EVs could offer anxiolytic, antidepressant, and sleep-inducing benefits by affecting neurotransmitter levels and reducing inflammation, particularly when administered intranasally.
July 2025 in “International Journal of Pharmaceutical Research and Development” This study evaluated a herbal oil derived from plant extracts for hair growth, finding it significantly accelerated hair growth in an animal model compared to controls, suggesting it as a natural and safe alternative to synthetic treatments with minimized side effects.
January 2023 in “International Journal of Trichology” In a case series, this study reported significant hair regrowth in both men and women with androgenetic alopecia using a topical hemp extract high in CBD, THCV, and CBDV over six months.
April 2018 in “Dermatologic Surgery” A new surgical technique using vellus hair grafts effectively treated vitiligo without causing unwanted hair growth.
August 2008 in “Pediatrics in Review” This review of literature on complementary and alternative medical therapies for pediatric asthma found mixed evidence, highlighting potential promise in treatments like ivy leaf extract and massage, but inconclusive or unsupported effects for others such as homeopathy and dietary modifications.
In this study, imaging techniques showed that nanostructured lipid carrier formulations distributed ascorbic acid more effectively across skin layers compared to conventional cream formulations, suggesting a better method for skin permeation.
32 citations
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March 2006 in “PubMed” This article reviews treatment options for unwanted facial hair in women, noting that eflornithine 13.9% cream reduces hair growth rate and can be combined with other methods.
September 2019 in “Journal of Investigative Dermatology” This study found that a combination of botanical extracts from Pisum sativum and Salvia hispanica reduced oxidative damage, re-balanced scalp oiliness, and improved scalp hydration and barrier function after pollution exposure.
1 citations
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January 2017 in “Ancient science of life/Ancient Science of Life” This study reported that Vatika Enriched Coconut Hair Oil was safe and more effective than regular coconut oil in reducing hair fall, controlling dandruff, and enhancing hair condition, such as shininess and tensile strength, in women over an 8-week period with no adverse effects.
January 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” This study found that EGCG, a compound from green tea, may enhance the proliferation and antioxidant activity of dermal papilla cells by upregulating VEGFA expression, potentially aiding hair follicle growth.
21 citations
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January 2006 in “Hormone Research in Paediatrics” In this case study, a girl with hereditary vitamin D resistant rickets had a novel mutation in the VDR gene that affected hair cycling without causing total alopecia, suggesting ligand-independent VDR function in hair cycling.
November 2018 in “Annals of oncology” This study found that the computer-controlled RV-01 scalp cooling device helped prevent significant hair loss in metastatic breast cancer patients treated with eribulin, with none of the 16 patients requiring a wig and experiencing minimal discomfort.
March 2025 in “Journal of Investigative Dermatology” In this survey study, 44% of epidermolysis bullosa patients who tried cannabinoids reported effective symptom management, particularly pain relief, but concerns about cost, stigma, and accessibility remain significant. Further research is necessary to confirm these findings and optimize cannabinoid therapies for EB.
10 citations
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September 2021 in “International Journal of Nanomedicine” This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.
8 citations
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June 2022 in “International Journal of Molecular Sciences” This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.
This literature review found a lack of scientific studies on whether apple cider vinegar rinses can reduce carcinogenic exposure from synthetic hair extensions, indicating a need for future research to explore this potential intervention.
December 2024 in “The Journal of Dermatology” 75 citations
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August 2006 in “International Journal of Pharmaceutics” The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.