Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that mutant mice with the we/we wal/wal genotype exhibit significant defects in hair shaft structure and epidermis stratification, correlating with postnatal alopecia symptoms.

This review discusses progeria, focusing on its pathogenesis, major symptoms, and management strategies, and includes a clinical case of a girl with the disease confirmed by genetic testing; it reports no new clinical results.

Skin cells can help create early hair-like structures in lab cultures.

In this study, researchers found that as androgenetic alopecia severity increased, the hair follicle matrix and dermal papilla's volume and cell nuclei number decreased, especially in the papilla.

This study found that matrix cells from normal hair follicles primarily had a 2C DNA content, while those in androgenetic alopecia showed a significant increase in cells with a higher DNA content.

This study on female Wistar rats with stress-induced alopecia found that a modified diet rich in antioxidants and nutrients reduced dystrophic skin changes and preserved the functional activity of hair follicles, suggesting dietary approaches may support hair restoration under chronic stress conditions.

This review suggests a shift toward genetically informed treatments for male pattern hair loss by integrating genetic insights and pharmacogenetic markers into therapeutic decision-making.

This study found that using platelet-rich plasma in optimal doses improves mesh integration and reduces the risk of chronic pain and fibrosis in hernia repair, but overdoses led to inflammatory complications in rats.

This review reports the potential therapeutic effects of Semecarpus anacardium Linn. (Bhallataka), noting its compounds like anacardic acid may have anti-inflammatory, antioxidant, and anticancer properties, but emphasizes that further research is necessary to confirm these effects and determine safety due to inconsistent study methods.

This study observed that Nigerian women with PCOS have significantly higher levels of myocardial biomarkers (MYO, cTnI, CK-MB), indicating potential chronic, subclinical myocardial injury in this population.

This study found that human hair shows progressive damage from UV and gamma radiation exposure, with fluorescence intensity serving as a sensitive measure of radiation-induced changes.

This study found that mesenchymal stem cells from chronically inflamed human livers maintain their key cellular characteristics, supporting their potential use in developing liver cell therapies.

This study found that both desmoglein-specific and non-desmoglein autoantibodies may play active roles in Pemphigus vulgaris pathogenesis, with HLA genetics influencing autoimmune specificity.

This study suggests that the Anetholea anisita extract improved scalp health by increasing specialized pro-resolving mediators and reducing pro-inflammatory markers, leading to decreased dandruff and enhanced hair brightness in dandruff sufferers.

This review summarizes existing evidence on how YAP and TAZ proteins are activated in epidermal keratinocytes and their role in coordinating with other signaling molecules to control transcription and influence epidermal cell fate, highlighting their importance beyond the Hippo pathway.

This study observed that cutaneous microwounds created by fractional photothermolysis heal differently from typical wounds, displaying rapid re-epithelialization and limited inflammation, which may help reduce scar formation by delaying collagen remodeling and minimizing myofibroblast activation.

Photocrosslinkable biomaterials can improve wound healing by controlling mechanical environments.

In this study, researchers found that disrupting desmoglein 3 signaling in a mouse model of pemphigus vulgaris activates normally quiescent hair follicle stem cells, compromising their multipotency but prompting a regenerative response that restores stem cell function and structures.

This study found that D-peptide crosslinked MAP hydrogel accelerated material degradation in vivo but significantly enhanced skin regeneration, suggesting an adaptive immune response can drive regenerative healing even with rapid scaffold breakdown.

These guidelines discuss prevention and management strategies for dermatological toxicities but report no new clinical results; they include expert recommendations for conditions like acneiform rash and hand-foot syndrome.

This study found that exosomes from different mesenchymal stem cell sources had distinct effects on immune cell functions and varied microRNA expression profiles compared to their original cells.

This study found that a multifunctional hydrogel dressing enriched with Cu-MOF and tannic acid significantly improved full-thickness wound healing in rats, reducing the wound area to only 1.6% and promoting re-epithelialization, neovascularization, and hair follicle formation.

This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.

In this study, researchers observed that more hairs are extracted from the follicle with intact root bulbs than breakage occurring along the fiber in treated versus untreated hair.

In this multicentric retrospective study, researchers reported that cutaneous adverse events were common among advanced breast cancer patients treated with cyclin-dependent kinase inhibitors (CDK4/6i), generally mild, and manageable with topical treatments, though in some cases, they led to treatment discontinuation.

This study developed a natural hair dye using Coreopsis tinctoria Nutt. extract, finding that it produced yellow to dark brown colors depending on the treatment, with ferrous lactate enhancing dye performance and color stability after washing.

This study developed a deep-learning model that accurately diagnosed alopecia areata with an accuracy of 88.92% and distinguished its activity levels with an accuracy of 83.33%, highlighting the potential for artificial intelligence in improving the diagnosis and treatment of this autoimmune hair loss condition.

In this Delphi study, international experts established consensus-based guidelines for diagnosing and managing persistent chemotherapy-induced alopecia (pCIA), recommending prevention through scalp cooling and early use of minoxidil, while advising against bicalutamide and certain finasterides for breast cancer patients due to safety concerns.

In this study, researchers identified three pathogenic de novo genetic variants contributing to epidermolysis bullosa simplex in young children, highlighting the complexity of genetic influences and underscoring the need for early genetic screening for accurate diagnosis and effective management.

This study observed that aluminum inhibits root hair growth in Limnobium stoloniferum, potentially by blocking calcium influx, although growth inhibition was also present at lower aluminum concentrations without affecting calcium flux.