TLDR Hair loss happens due to faster cell growth and fewer cells in affected follicles.
This study analyzed the DNA content of hair follicles in normal scalp and in scalps affected by androgenetic alopecia. The study found that affected follicles experience an acceleration of the mitotic rhythm, leading to an increase in hair in telogen and a widening difference in the anagen/telogen relationship. The decrease in the total number of cells within the matrix and papilla, combined with the acceleration of the cell cycle, leads to irreversible involution of the hair follicle.
19 citations,
August 1993 in “Journal of Cutaneous Pathology” Alopecia causes smaller hair follicles and affects growth-related structures.
37 citations,
January 1987 in “Dermatology” Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
58 citations,
January 1987 in “Archives of Dermatological Research” EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.
90 citations,
October 1983 in “British Journal of Dermatology” The unit area trichogram is a reliable method to assess hair loss and treatment response in people with androgenic alopecia by measuring hair density and thickness.
3 citations,
November 2018 in “PubMed” SMT effectively treats advanced baldness with high satisfaction.
1 citations,
August 1994 in “Journal of Cutaneous Pathology” Hair loss happens due to faster cell growth and fewer cells in affected follicles.
3 citations,
July 1987 in “Dermatologic Clinics” Scalp reduction can treat severe hair loss, but success depends on scalp flexibility and it may cause complications like pain, infection, and cosmetic issues.
