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    Morphological Changes in the Skin in a Rat Model of Stress-Induced Alopecia and Their Correction with Nutrients

    June 2026 in “ Reports of Morphology
    R. R. Kovalevych, T. V. Valivko, Соломія Крамар … О. Z. Yaremchuk
    Studysummary This study on female Wistar rats with stress-induced alopecia found that a modified diet rich in antioxidants and nutrients reduced dystrophic skin changes and preserved the functional activity of hair follicles, suggesting dietary approaches may support hair restoration under chronic stress conditions.
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    Research cited in this study 13

    1. Corticotropin-Releasing Hormone Inhibits Autophagy by Suppressing PTEN to Promote Apoptosis in Dermal Papilla Cells Annals of Medicine · 2025
    2. Oxidative Stress in Hair Follicle Development and Hair Growth: Signaling Pathways, Intervening Mechanisms and Potential of Natural Antioxidants Journal of Cellular and Molecular Medicine · 2024
    3. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    4. Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways International journal of molecular sciences · 2023
    5. Mild Oxidative Stress Protects Against Chemotherapy-Induced Hair Loss Frontiers in Oncology · 2023
    6. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022
    7. Vitamin A Alleviates Heat Stress-Induced Damage to Hair Follicle Development in Rex Rabbits Journal of the Science of Food and Agriculture · 2021
    8. Glutamic Acid Promotes Hair Growth in Mice Scientific Reports · 2021
    9. Immunology of Alopecia Areata Central-European Journal of Immunology/Central European Journal of Immunology · 2020
    10. Telogen Effluvium: A Review of the Literature Cureus · 2020
    11. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
    12. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    13. Chronic Restraint Stress Inhibits Hair Growth via Substance P Mediated by Reactive Oxygen Species in Mice PLoS ONE · 2013