Vitamin A Alleviates Heat Stress-Induced Damage to Hair Follicle Development in Rex Rabbits

    October 2021 in “ Journal of the Science of Food and Agriculture ”
    Zhengkai Yue, Chenyang Li, Yongxu Liu, Mengqi Liu, Man Zhao, Fuchang Li, Lei Liu
    TLDR Vitamin A improves fur quality in heat-stressed Rex rabbits.
    The study investigated the impact of dietary vitamin A (VA) on hair follicle development in Rex rabbits under heat stress, involving 90 rabbits divided into three groups. Results showed that VA significantly improved hair follicle density, hair length, and the ratio of secondary to primary hair follicles in heat-stressed rabbits. VA also modulated several signaling pathways, including Wnt10/β-catenin, IGF1, FGF5, noggin-BMP, and SHH, by altering the expression of related genes and proteins. The findings suggested that VA could enhance fur quality in heat-stressed Rex rabbits, with potential contributions from miR-205 and miR-194 in regulating these pathways.
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