Allohernioplasty With the Introduction of Platelet-Rich Plasma in a Chronic Experiment: Features of the Reparative Process

    May 2025 in “ Ambulatornaya khirurgiya = Ambulatory Surgery (Russia) ”
    L. O. Severgina, М. Р. Кузнецов, О. Н. Антонов, K. A. Dmitrieva, A. N. Kosenkov, G. V. Sinyavin, M.E. Shakhbanov, D. A. Gasparyan, S. A. Kolomytseva, L. A. Milenkii
    Image of study
    TLDR Optimal PRP dosage improves healing and reduces complications in hernia repair.
    The study investigated the effects of platelet-rich plasma (PRP) on the reparative process in allohernioplasty using 47 Wistar rats. The rats were divided into three groups: optimal PRP dosage, maximum PRP dosage, and no PRP. Results showed that the optimal PRP dosage improved mesh implant integration, prevented rough fibrosis, and reduced the likelihood of chronic pain syndrome. Morphological analysis revealed better vascularization, early formation of a delicate scar, and minimal nerve degeneration. However, excessive PRP dosage led to destructive-inflammatory reactions and chronic abscesses due to excessive neutrophil and macrophage activity.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 105 results

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  12 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 11 months ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Microneedling versus Platelet-Rich Plasma

      in Research/Science  5 upvotes 1 day ago
      Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

      community Why can't you drink caffeine after PRP?

      in Treatment  10 upvotes 3 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  552 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

    Similar Research

    5 / 1000+ results