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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

TSH is usually the only test needed to check thyroid function in primary care.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Lower hair zinc and copper levels found in Turkish males with hair loss; higher BMI linked to less hair zinc.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.

Measuring plasma testosterone glucosiduronate is a reliable way to detect high male hormone levels in women.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.

Zinc levels in body fluids can help diagnose zinc deficiency in lambs, with fecal zinc as an early indicator.

New genes and pathways are important for testosterone production and male sexual development.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Cosmetic hair treatments can increase hair testosterone levels, while natural hair color does not affect it.

Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.

Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.

A new method was created to analyze certain chemicals in the urine of alopecia areata patients, revealing they have higher metanephrine content. This method can also be used for other related diseases.