research Gerbils
Proper care and diet are crucial to prevent health issues in gerbils.
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research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Prostatic Cystic Hyperplasia in a Young Dog: Case Report
A young dog with an enlarged prostate and cysts improved significantly after treatment and surgery.
research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor
Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
research Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Clinical Effects and Economic Impact of Dutasteride and Finasteride Therapy in Italian Men with Lower Urinary Tract Symptoms
Dutasteride reduces hospitalization and prostate cancer risk compared to finasteride, potentially offsetting its higher cost.
research 5-Alpha-Reductase Inhibitors for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Obstruction
5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
research Differential Expression of Retinoic Acid-Synthesizing (RALDH) Enzymes During Fetal Development and Organ Differentiation in the Mouse
Different enzymes are active in different parts of developing mouse organs.
research Development and Validation of a Reversed-Phase HPLC Method for Simultaneous Determination of Doxazosin Mesylate and Finasteride
Created method to measure doxazosin mesylate and finasteride together.
research Inhibitory Effects of the ATP-Sensitive Potassium Channel Openers Cromakalim, Pinacidil, and Minoxidil on the Carbachol-Response Curve in Porcine Detrusor Muscle
Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
research Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform
Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.
research Sexuality and Old Age
Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
research Anti-Inflammatory Effects in LPS-Treated RAW 264.7 Cells and the Influences on Drug Metabolizing Enzyme Activities by the Traditional Herbal Formulas, Yongdamsagan-Tang and Paljung-San
The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Spermatozoa and Chronic Treatment with Finasteride: A TEM and FISH Study
Finasteride may negatively affect male fertility.
research Adult Patients with Aphallia: Were They Fertile?
The document does not determine if adults with aphallia are fertile.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research External Genitalia Abnormalities in Male Rats Exposed In Utero to Finasteride, a 5α-Reductase Inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
research 5-Alpha-Reductase Type 2 Deficiency: Is There a Genotype-Phenotype Correlation? A Review
No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
research Epidermal Stem Cells in Wound Healing and Their Clinical Applications
Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
research Dermatologic Care of the Transgender Patient
Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.
research Clinical Review of Ejaculatory Dysfunction
The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
research A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)
Finasteride may help some male chronic pelvic pain patients, but more research needed.
research Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors
Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.