4 citations
,
April 2016 in “Journal of Dermatology Research and Therapy” This article discusses the multifactorial nature of acne vulgaris, detailing its link to androgen-induced sebum production, altered keratinisation, inflammation, and bacterial colonisation, but reports no new research findings.
4 citations
,
December 2013 in “Acupuncture and related therapies” This review summarizes the potential of N-acetyl-cysteine in managing diseases linked to redox imbalance, discussing its effects from cellular mechanisms to clinical applications, though further research is suggested for broader use.
37 citations
,
May 1997 in “The Journal of Clinical Endocrinology & Metabolism” This study found that MK-386 selectively suppressed sebum DHT levels in a dose-dependent manner, suggesting potential use for treating acne.
2 citations
,
January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that Hataedock may alleviate atopic dermatitis symptoms in mice by maintaining skin homeostasis and improving skin barrier formation through the endocannabinoid system.
This study synthesized new heterocyclic steroid derivatives and reported their promising antiproliferative activity against breast and prostate cancer cell lines, highlighting selectivity and impact on signaling pathways even in cells resistant to certain treatments.
14 citations
,
August 2009 in “Cancer epidemiology” This study found that AHCC significantly reduced alopecia caused by Ara-C in neonatal rats and improved liver function affected by 6-MP and MTX in mice.
October 2010 in “Reproductive Biomedicine Online” This study reported that MALDI-TOF Mass Spectrometry profiling demonstrated nearly 100% sensitivity and specificity in detecting adenomyosis and leiomyoma, revealing potential peptide markers for these conditions.
1 citations
,
February 2025 in “Toxicology in Vitro” In this study, DPHC from the brown alga Ishige okamurae demonstrated potential to prevent androgenic alopecia by inhibiting hair loss and promoting hair growth through multiple cellular mechanisms.
69 citations
,
December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
February 2009 in “Endocrinology” This study evaluated the use of oral DHEA for treating atrichia pubis and psychological distress in young females with central adrenal insufficiency but reports no new results.
November 2025 in “Drug Testing and Analysis” This study investigated the metabolic pathways of epristeride, a new Type II 5α‐reductase inhibitor, using in vitro models and found that its metabolites show significant interactions with key proteins, suggesting implications for its role in doping control.
1 citations
,
November 2023 in “Indian Journal of Science and Technology” In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.
October 2025 in “BMC Pediatrics” This case report describes an 8-year-old boy with acrodermatitis enteropathica who showed significant recovery from severe symptoms after receiving a therapeutic zinc supplement.
March 2025 in “Carbohydrate Polymer Technologies and Applications” In this study, researchers developed a carboxylated β-cyclodextrin formulation to enhance finasteride's physicochemical properties, achieving an encapsulation efficiency of about 85% and indicating potential for controlled drug release in therapeutic applications. Their findings suggest this inclusion complex could improve delivery of hydrophobic drugs like finasteride.
September 2026 in “Portuguese Journal of Dermatology and Venereology” In this review, the researchers discuss the potential effectiveness of azelaic acid peels for treating acne vulgaris, melasma, and other skin conditions, while acknowledging that the precise role of these peels in dermatology is not yet fully established due to limited studies.
4 citations
,
May 2018 in “Türk pediatri arşivi : İstanbul çocuk kliniği dergisi” This study reported dramatic improvements in five collodion baby patients with lamellar ichthyosis treated with oral retinoic acid, noting hair loss as the sole adverse effect, emphasizing the treatment's promising efficacy for physicians.
14 citations
,
February 1994 in “Tetrahedron Letters” This study found that using anhydrous cerium(III) chloride with alkyl Grignard reagents significantly improved the addition to sterically hindered 17-ketosteroids, resulting in high yields and stereoselectivity.
2 citations
,
March 2017 in “Asian Journal of Beauty and Cosmetology” This study found that caffeic acid reduced UVB-induced damage and oxidative stress in human dermal papilla cells, suggesting its protective efficacy against such cellular damage.
7 citations
,
April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.
March 2023 in “Journal of Applied Biomedicine” This study suggests that oleanolic acid may promote hair growth in mice with testosterone-induced androgenetic alopecia by activating the Wnt/β-catenin pathway and influencing various molecular levels.
August 2016 in “Journal of Investigative Dermatology” This study suggests that enhancing endocannabinoid tone with an EMT-inhibitor may have anti-inflammatory effects and slightly increase sebaceous lipid production, which could be beneficial for dry skin conditions.
5 citations
,
December 2014 in “Medicine and Pharmacy Reports” This study found that antiandrogenic therapy with Melleva 35 for three months was effective in reducing hair loss and improving acne in women with both Androgenetic Alopecia and Acne Vulgaris.
11 citations
,
June 2016 in “European Journal of Medicinal Chemistry” This study found that two synthesized androst-4-ene-3-one derivatives, 6f and 6g, exhibited stronger anti-proliferative effects than common drugs on prostate cancer cell lines, with low toxicity to rat cells.
4 citations
,
May 2014 in “Pharmaceutical Biology” This study found that topical application of glycyrrhizic acid led to significant hair removal in rats without causing inflammation, suggesting potential for treating hypertrichosis in humans.
4 citations
,
January 2017 in “Biological & pharmaceutical bulletin” This study found that inhibiting arachidonate 12-lipoxygenase (ALOX12) may enhance hair cuticle maturation by increasing S100A3 protein citrullination and promoting cuticular differentiation in isolated human hair follicles.
24 citations
,
March 2022 in “Journal of the American Academy of Dermatology” Adalimumab improved folliculitis decalvans in most patients.
October 2009 in “Reactions Weekly” A woman developed lupus after taking hydroxyurea for two years.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no elevation of serum DHEA-S levels in men with androgenetic alopecia and observed no correlation between DHEA-S levels and the clinical stage of the condition.
July 2008 in “International journal of psychophysiology” This retrospective study found that cyproterone acetate, both alone and with estrogens, was safe, well tolerated, and induced modest feminizing effects in late-pubertal transgender female adolescents.
March 2014 in “Journal of The American Academy of Dermatology” Mycophenolic acid may help hair grow by activating pathways important for hair growth.