Triglyceridemia in Conditions of Food Stress in Women with Polycystic Ovary Syndrome and Androgenic Alopecia

    October 2010 in “ Reproductive Biomedicine Online
    A. V. Strelkova, I.N. Zykov, L.B. Koptyaeva, T.A. Zykova
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    TLDR Women with PCOS and androgenic alopecia have different triglyceride metabolism compared to those without hair loss.
    The document reports on a study that investigated the relationship between triglyceride metabolism and androgenic dermopathy, including androgenic alopecia, in women with polycystic ovary syndrome (PCOS). The study included 66 women aged 18-35 years, divided into groups based on the presence and severity of androgenic dermopathy. The participants underwent a fat loading test, and their triglyceride levels were measured at fasting, and 3, 9, and 24 hours post-consumption. The results showed significant differences between groups in postprandial 3-hour triglyceride levels, growth rate, and elimination of triglycerides. Women with alopecia had lower 3-hour triglyceride levels, slower growth rates, and slower elimination rates compared to those without alopecia. The study concluded that the phenotypic variety in PCOS and the appearance of androgenic dermopathy and alopecia are influenced not only by androgen activity but also by differences in triglyceride absorption and transport.
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