Into the Redox Control: N-Acetyl-Cysteine Pleiotropic Effects from the Laboratory to Clinical Applications

    December 2013 in “ Acupuncture and related therapies ”
    Tiziana Parasassi, Roberto Brunelli, Ewa K. Krasnowska, Thomas Lundeberg, Eugenia Pittaluga, Maria Romano
    Image of study
    TLDR N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.
    The document from 2014 explores the therapeutic potential of N-acetyl-cysteine (NAC) in redox regulation and its effects on various diseases, including cancer, endometriosis, and dermatological conditions like alopecia and vitiligo. It reports that NAC can induce differentiation and inhibit proliferation in both normal and cancer cells, potentially through its interaction with thiol redox switches. In a murine model of endometriosis, NAC treatment resulted in a significant decrease in endometriomas mass and reduced cell proliferation. A clinical study with 47 endometriosis patients showed a small reduction in ovarian cysts dimension after three months of NAC treatment without adverse effects. Additionally, preliminary case studies indicated that a combination of NAC with melatonin and selenomethionine might improve skin conditions and promote hair regrowth in alopecia universalis. However, the document emphasizes the need for further studies to determine optimal dosages, treatment modalities, and to understand the long-term effects of such treatments.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 573 results

      community Nothing's working, I feel depressed, also hopeless for the first time

      in Update  101 upvotes 3 years ago
      A user's experience with hair loss treatments, including Finasteride, Minoxidil, Nizoral Shampoo, Rosemary Oil, Vitamin D, Biotin, Vitamin C, Zinc and Dermarolling, that have not been successful over the past 14 months. Other users gave advice on how to cope with the issue, such as exercising, changing mindset, and shaving their head.

      community Let Me Sell You on NAC

       17 upvotes 6 years ago
      The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

      community Fighting Hair loss AND Grey Hair

      in Treatment  2 upvotes 3 years ago
      OP is exploring ways to stop or reverse greying hair, using NAC and considering PABA supplements. Some users suggest hair dye, black strap molasses, and copper as potential solutions.

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 1 year ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

    Similar Research

    6 / 1000+ results