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AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.

Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

SLE and DM can coexist but are rare and need careful evaluation.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Kartogenin may help treat hair loss by promoting hair growth and extending the hair growth phase.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

Chicken feather gene mutation helps understand human hair disorders.

Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.

Nutrease powder, a high-protein, low-carb supplement, can help manage Polycystic Ovary Syndrome symptoms, regulate periods, improve ovulation, and restore fertility.

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Interleukin-1 increases keratin K6 production in skin cells.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.