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The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Some common medications can harm male fertility, but many effects can be reversed.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.

Breadfruit is nutritious and has potential health and medicinal benefits, but is currently underused.

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The conclusion is that more hair loss (androgenetic alopecia) is linked to larger prostate size, suggesting hair loss could be an early sign of benign prostatic hyperplasia.

Teak leaf extract hair tonic was tested for hair growth and safety.

Hydrangea serrata extract may promote hair growth and improve hair health.

RE-ORGA, a Korean herb extract, may help prevent hair loss.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Sphinganine can reduce hair loss and improve scalp health.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Finasteride exposure harms tadpole reproduction and hormone balance.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Dutasteride is the most effective hair loss treatment after 24 weeks, but finasteride leads to the most hair growth after 48 weeks.