An Observational Study of the Association Between Androgenetic Alopecia and Size of the Prostate

January 2016 in “ International Journal of Trichology ”

Kanagaraj Ramsamy, Radhakrishnan Subramaniyan, Anjan Kumar Patra

androgenetic alopecia benign prostatic hyperplasia 5-alpha reductase inhibitors AGA BPH

TLDR The conclusion is that more hair loss (androgenetic alopecia) is linked to larger prostate size, suggesting hair loss could be an early sign of benign prostatic hyperplasia.

This document is an observational study that aimed to establish the relationship between androgenetic alopecia (AGA) and the size of the prostate. The study included 65 male patients with AGA, and it found that as the grade of AGA increased, there was an increase in the size of the prostate. The study suggests that AGA may serve as an early marker for benign prostatic hyperplasia (BPH). However, further research is needed to better understand this association and to evaluate the potential benefits of treating AGA with 5-alpha reductase inhibitors in delaying the onset of BPH.

View this study on ijtrichology.com →

Discuss this study in the Community →

Research cited in this study

6 / 6 results

research The Endocrinology of Baldness

19 citations, April 2014 in “Hormones”

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

research Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia

5 citations, November 2012 in “The Journal of Urology”

Early hair loss may indicate future prostate issues.

research Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia

28 citations, August 2011 in “Journal of The American Academy of Dermatology”

Early hair loss may indicate prostate issues.

research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia

33 citations, October 2004 in “Archives of Dermatological Research”

Large prostate links to more hair loss, but age of onset doesn't affect it.

research Androgenetic Alopecia and Prostate Cancer: Findings from an Australian Case-Control Study

21 citations, June 2002 in “PubMed”

The conclusion is that there might be a link between certain types of baldness and prostate cancer, which could be due to shared hormonal pathways.

research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness

54 citations, May 1998 in “Urology”

Men with enlarged prostates often have more severe baldness.

Related Community Posts Join

6 / 1000+ results

community FCE 28260: A Forgotten 5α-Reductase Inhibitor

in Research 330 upvotes 7 months ago

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 1 year ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.

in Research/Science 155 upvotes 3 months ago

GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 103 upvotes 3 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

Related Research

4 / 4 results

research Can We Predict Prostate Size by Scoring Baldness? The Relationship of Androgenic Alopecia and Lower Urinary Tract Symptoms

1 citations, January 2019 in “PubMed”

Baldness score can't be used to predict prostate size.

research Association Between Degrees of Alopecia and Prostate Specific Antigen Level in Men With Androgenetic Alopecia

January 2018 in “프로그램북(구 초록집)”

No link between hair loss severity and PSA levels in men.

research One Year Cross-Sectional Study of Association Between Androgenetic Alopecia and Benign Prostatic Hyperplasia in a Tertiary Care Hospital

January 2017 in “Indian journal of health sciences and biomedical research KLEU”

There is no link between hair loss and prostate enlargement.

research Is There a Relationship Between Androgenic Alopecia and Benign Prostatic Hyperplasia?

3 citations, January 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)”

There's no link between hair loss type androgenic alopecia and benign prostatic hyperplasia, but early hair loss and family history can mean more severe alopecia.