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MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

The study created a new method to test drugs that affect hormone processing in skin.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride cream helps hair growth with less side effects.

Solanum nigrum extract may help regrow hair.

Finasteride effectively reduces hair loss by decreasing androgen levels.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The review suggests there's no agreed treatment for Frontal Fibrosing Alopecia, but hydroxychloroquine and 5a-reductase inhibitors are most effective. New treatments like platelet-rich plasma and LED light could help if standard treatments fail.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Rats had lasting erectile problems after stopping a certain medication.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.