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Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces movement issues in Parkinson's disease rats.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

Eclipta alba extract could be a promising natural treatment for hair loss.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride helps reduce pain and inflammation in animals.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Solanum nigrum extract may help regrow hair.

Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.

Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

Created microspheres show potential for safe and effective use in prostate artery embolization.

Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.