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Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Gene mutations can cause problems in male genital development.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Testosterone may slow down wound healing and increase inflammation.

Better hair loss models needed for research.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Nepenthes kampotiana extract can potentially prevent hair loss and could be an effective treatment for common baldness.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.

The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.

Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Finasteride may cause kidney damage.