Therapeutic Effect of Nepenthes Kampotiana Lecomte Ethanol Extract on Androgenic Alopecia through the Inhibition of Apoptosis and 5α-Reductase Activity

    August 2023
    Dong Seon Kim, Won Young Jang, Sang Hee Park, Ji Hye Yoon, Chae Yun Shin, Lei Huang, Kry Masphal, Phourin Chhang, Hye-Woo Byun, Jung-Ho Son, Ga Ryun Kim, Byoung-Hee Lee, Jong-Hoon Kim, Jongsung Lee, Jae Youl Cho
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    TLDR Nepenthes kampotiana extract can potentially prevent hair loss and could be an effective treatment for common baldness.
    The study investigates the potential of Nepenthes kampotiana Lecomte ethanol extract (Nk-EE) in treating androgenic alopecia, a common form of hair loss. The research found that Nk-EE promotes the proliferation of human follicle dermal papilla cells and inhibits cell death, suggesting its potential in preventing hair loss. In vivo experiments using androgenic areata models demonstrated that Nk-EE positively impacted various biomarkers such as hair-to-skin ratio, hair type frequency, and hair thickness. These findings suggest that Nk-EE could be an effective treatment for androgenic alopecia.
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