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Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

New oral treatment, finasteride, effectively and safely treats common hair loss.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Excess androgens may cause PCOS, not just be a symptom.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Effective PCOS treatments require targeting specific signaling pathways.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Finasteride may cause slight depression and anxiety.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Mutant mice help researchers understand hair growth and related genetic factors.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.