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The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Mutant mice help researchers understand hair growth and related genetic factors.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

New genes and pathways are important for testosterone production and male sexual development.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Finasteride reduces hair growth and is safe for women with excessive hair.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride can cause sexual problems and depression in young men.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

PCOS is a long-term condition that needs more research for better understanding and treatment.