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No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

Sex-determining genes may affect male baldness.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

Finasteride effectively reduces hair loss by decreasing androgen levels.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

ADM scaffolds help skin heal by promoting a healing-type immune response.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Alopecia Areata is a complex, unpredictable autoimmune hair loss condition with limited treatment options and a significant psychological impact.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Sex hormones, especially androgens, play a key role in causing acne.

Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Trazodone might help reverse post finasteride syndrome.